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静脉补液复苏对低血压猫的疗效:82 例病例报告(2012-2019 年)。

Effectiveness of intravenous fluid resuscitation in hypotensive cats: 82 cases (2012-2019).

机构信息

Department of Clinical Sciences & Advanced Medicine, University of Pennsylvania, School of Veterinary Medicine, Philadelphia, Pennsylvania, USA.

出版信息

J Vet Emerg Crit Care (San Antonio). 2021 Jul;31(4):508-515. doi: 10.1111/vec.13075. Epub 2021 May 20.

DOI:10.1111/vec.13075
PMID:34014600
Abstract

OBJECTIVE

To evaluate the effectiveness of intravenous fluid resuscitation in hypotensive cats in an emergency room setting. Secondary objectives were to investigate changes in heart rate (HR) and body temperature (BT) in response to fluid resuscitation, and the association of these changes with patient survival.

DESIGN

Retrospective study.

SETTING

University teaching hospital.

ANIMALS

Eighty-two cats with confirmed hypotension.

INTERVENTIONS

None.

MEASUREMENTS AND MAIN RESULTS

Medical records from 2012 to 2019 were searched for cats that had documented systemic arterial hypotension (blood pressure measured using a Doppler ultrasonic flow probe [DBP] < 90 mm Hg) on presentation to the emergency room. Data collected included patient characteristics and DBP, HR, and BT before and after fluid resuscitation, type and volume of fluids administered, and outcome. The median DBP before and after resuscitative fluid therapy in all cats was 65 mm Hg (range, 20-85 mm Hg) and 80 mm Hg (range, 20-128 mm Hg), respectively (P < 0.001). However, only 30 cats (37%) were classified as responders to fluid resuscitation (DBP ≥ 90 mm Hg following bolus therapy). The mean HR and median BT before resuscitative fluid therapy was 159/min and 36.7°C. Following fluid resuscitation, where measured, the mean HR and median BT was 154/min (P = 1.00) and 35.9°C (P = 1.00). No significant differences in HR and BT were identified between responders and non-responders. Cats had a low survival rate of 7%. All survivors (n = 5) were initially bradycardic (HR < 160/min), compared to only 45% of non-survivors (P = 0.4).

CONCLUSIONS

Bolus fluid resuscitation effectively increases blood pressure in hypotensive cats; however, it does not result in normalization of blood pressure, HR, or BT in the majority of cases.

摘要

目的

评估在急诊环境中低血压猫进行静脉补液复苏的效果。次要目标是研究心率(HR)和体温(BT)对液体复苏的反应变化,并研究这些变化与患者生存的关系。

设计

回顾性研究。

设置

大学教学医院。

动物

82 只确诊低血压的猫。

干预

无。

测量和主要结果

2012 年至 2019 年,检索了在急诊就诊时记录有系统动脉低血压(使用多普勒超声流量探头[DBP]测量血压<90mmHg)的猫的病历。收集的数据包括患者特征以及液体复苏前后的 DBP、HR 和 BT、给予的液体类型和体积以及结果。所有猫的中位 DBP 在复苏性液体治疗前后分别为 65mmHg(范围 20-85mmHg)和 80mmHg(范围 20-128mmHg)(P<0.001)。然而,只有 30 只猫(37%)被归类为液体复苏的反应者(补液治疗后 DBP≥90mmHg)。在进行复苏性液体治疗之前,平均 HR 和中位数 BT 分别为 159/min 和 36.7°C。在进行液体复苏后,测量的平均 HR 和中位数 BT 分别为 154/min(P=1.00)和 35.9°C(P=1.00)。在反应者和非反应者之间,HR 和 BT 没有显著差异。猫的存活率很低,为 7%。所有存活者(n=5)最初均为心动过缓(HR<160/min),而只有 45%的非存活者(P=0.4)。

结论

在低血压猫中,单次补液复苏可有效升高血压;然而,在大多数情况下,它不会导致血压、HR 或 BT 恢复正常。

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