Silverstein Deborah C, Kleiner Jennifer, Drobatz Kenneth J
Matthew J. Ryan Veterinary Hospital, Department of Clinical Studies-Philadelphia, University of Pennsylvania, Philadelphia, PA 19104-6010, USA.
J Vet Emerg Crit Care (San Antonio). 2012 Dec;22(6):666-73. doi: 10.1111/j.1476-4431.2012.00822.x.
To assess the effectiveness of fluid resuscitation for the treatment of hypotensive dogs presented to the emergency room.
Retrospective study (2000-2010).
University teaching hospital.
Thirty-five dogs with confirmed hypotension.
None.
Medical records from 2000 to 2010 were searched for dogs that had documented arterial hypotension (Doppler blood pressure <90 mm Hg) upon presentation to the emergency room. The following data were collected for retrospective analysis: signalment, body weight, systolic blood pressure (BP) and heart rate (HR) before and after fluid resuscitation, type and volume of fluid administered within the first hour of hospitalization, presence or absence of confirmed sepsis, and outcome. There was a significant increase in BP following fluid resuscitation and 23 dogs showed normalization of blood pressure (Doppler blood pressure >90 mm Hg) following bolus IV fluid therapy within 1 hour of presentation. Fluid responsive animals were significantly less likely to be euthanized compared to those animals that did not respond to a fluid bolus (P = 0.013). The HR did not change significantly in either group postbolus therapy. Twenty-three dogs (65.7%) in the study received only isotonic crystalloid therapy, 11 dogs were administered both isotonic crystalloids and synthetic colloids, and 1 dog received only synthetic colloid resuscitation. A significant difference was not detected between groups with respect to type or volume of fluid administered.
Bolus fluid therapy for the treatment of hypotensive dogs resulted in increased in systolic arterial BP in all dogs, although the HR did not reliably decrease as might be expected. Dogs that showed normalization of BP within the first hour of fluid resuscitation were more likely to be discharged alive than those who remained hypotensive. A majority of dogs received and responded to isotonic crystalloids fluid resuscitation.
评估液体复苏对急诊室就诊的低血压犬的治疗效果。
回顾性研究（2000 - 2010年）。
大学教学医院。
35只确诊为低血压的犬。
无。
检索2000年至2010年的病历，查找急诊室就诊时记录有动脉低血压（多普勒血压<90 mmHg）的犬。收集以下数据进行回顾性分析：特征、体重、液体复苏前后的收缩压（BP）和心率（HR）、住院后第一小时内给予的液体类型和体积、是否确诊败血症以及结局。液体复苏后BP显著升高，23只犬在就诊后1小时内静脉推注液体治疗后血压恢复正常（多普勒血压>90 mmHg）。与未对液体推注产生反应的动物相比，对液体有反应的动物实施安乐死的可能性显著降低（P = 0.013）。推注治疗后两组的HR均无显著变化。研究中的23只犬（65.7%）仅接受等渗晶体液治疗，11只犬同时接受等渗晶体液和合成胶体液治疗，1只犬仅接受合成胶体液复苏。在给予的液体类型或体积方面，各组之间未检测到显著差异。
对低血压犬进行推注液体治疗可使所有犬的收缩动脉血压升高，尽管HR并未如预期那样可靠地降低。在液体复苏后第一小时内血压恢复正常的犬比仍处于低血压状态的犬更有可能存活出院。大多数犬接受了等渗晶体液复苏并产生了反应。
