Rotman Research Institute, Baycrest Health Sciences, 3560 Bathurst Street, Toronto, ON M6A 2E1, Canada; Department of Psychology, University of Toronto, 100 St. George Street, Toronto, ON M5S 3G3, Canada.
Neuron. 2021 Jul 21;109(14):2239-2255. doi: 10.1016/j.neuron.2021.04.025. Epub 2021 May 19.
Memory systems consolidation is often conceived as the linear, time-dependent, neurobiological shift of memory from hippocampal-cortical to cortico-cortical dependency. We argue that contrary to this unidirectional view of memory reorganization, information about events may be retained in multiple forms (e.g., event-specific sensory-near episodic memory, event-specific gist information, event-general schematic information, or abstract semantic memory). These representations can all form at the time of the event and may continue to coexist for long durations. Their relative strength, composition, and dominance of expression change with time and experience, with task demands, and through their dynamic interaction with one another. These different psychological mnemonic representations depend on distinct functional and structural neurobiological substrates such that there is a neural-psychological representation correspondence (NPRC) among them. We discuss how the dynamics of psychological memory representations are reflected in multiple levels of neurobiological markers and their interactions. By this view, there are only variations of synaptic consolidation and memory dynamics without assuming a distinct systems consolidation process.
记忆系统巩固通常被认为是记忆从海马体-皮质到皮质-皮质依赖的线性、时间依赖的神经生物学转变。我们认为，与记忆重组的这种单向观点相反，关于事件的信息可能以多种形式保留（例如，特定于事件的感觉近景情节记忆、特定于事件的主旨信息、事件一般性图式信息或抽象语义记忆）。这些表示形式都可以在事件发生时形成，并可能持续共存很长时间。它们的相对强度、组成和表达优势会随着时间和经验、任务需求以及彼此之间的动态相互作用而变化。这些不同的心理记忆表示依赖于不同的功能和结构神经生物学基质，因此它们之间存在神经-心理表示对应关系（NPRC）。我们讨论了心理记忆表示的动态如何反映在多个神经生物学标记及其相互作用的水平上。从这个角度来看，只有突触巩固和记忆动态的变化，而不假设存在一个独特的系统巩固过程。
