Lavrovskiĭ V A, Ustinov A S
Biull Eksp Biol Med. 1988 Jul;106(7):88-91.
The mouse CBA sarcoma characterized by great cellular heterogeneity was obtained from spontaneously in vitro transformed embryonic fibroblasts. The clones of the given sarcoma distinct in this property were studied. It was shown that the only feature limiting the growth of clones characterized by weak tumorigenicity was contact inhibition of cellular growth. This property is easily estimated by the in vitro methods.
以细胞高度异质性为特征的小鼠CBA肉瘤，是从体外自发转化的胚胎成纤维细胞中获得的。对该肉瘤在这一特性上存在差异的克隆进行了研究。结果表明，限制致瘤性弱的克隆生长的唯一特征是细胞生长的接触抑制。这一特性可通过体外方法轻松评估。
