超声刀联合内给氧辅助硝普钠在老年急性胆囊炎患者腹腔镜胆囊切除术中的应用
Ultrasonic scalpel combined with internal oxygen assisted sodium nitroprusside in laparoscopic cholecystectomy for elderly patients with acute cholecystitis.
作者信息
Huang Liang, Yu Jing, Zhu Jianghua
机构信息
Shanghai Tenth People's Hospital Shanghai 200072, China.
出版信息
Am J Transl Res. 2021 Apr 15;13(4):3093-3101. eCollection 2021.
UNLABELLED
To analyze the application value of an ultrasonic scalpel combined with internal oxygen assisted intravenous drip of sodium nitroprusside in laparoscopic cholecystectomy for elderly patients with acute cholecystitis.
METHODS
A total of 76 patients with acute cholecystitis who were admitted to our hospital from January 2017 to December 2018 were included and equally divided into two groups. The control group was treated with ultrasonic scalpel alone, while the study group was treated with ultrasonic scalpel combined with internal oxygen and intravenous drip of sodium nitroprusside. The incidence of postoperative adverse reactions, the recovery of surgical indicators, the quality of life score before and after treatment, and the changes of serum sICAM-1 and IL-6 expression were observed.
RESULTS
The incidence of postoperative adverse reactions in the study group was significantly higher than that in the control group (P < 0.05); and the recovery of surgical indicators in the study group was better than that in the control group (P < 0.05). After treatment, the levels of serum sICAM-1 and IL-6 in the two groups showed a certain degree of decline, and the levels of serum sICAM-1 and IL-6 inflammatory factors in the study group were significantly lower than those in the control group (P < 0.05). After treatment, the scores of psychological state, physical health, independent ability, social relationship, surrounding environment and personal belief of the two groups were significantly higher than those before treatment (P < 0.05). After treatment, the scores of each field in the treatment group were significantly higher than that in the control group (P < 0.05).
CONCLUSION
It is safe and feasible to use an ultrasonic scalpel combined with internal oxygen to assist intravenous drip of sodium nitroprusside in the treatment of elderly patients with acute cholecystitis, but proper operation time and skilled operation are necessary.
未标注
分析超声刀联合内给氧辅助硝普钠静脉滴注在老年急性胆囊炎腹腔镜胆囊切除术中的应用价值。
方法
选取2017年1月至2018年12月我院收治的76例急性胆囊炎患者，将其平均分为两组。对照组单纯采用超声刀治疗，研究组采用超声刀联合内给氧及硝普钠静脉滴注治疗。观察术后不良反应发生率、手术指标恢复情况、治疗前后生活质量评分以及血清sICAM-1和IL-6表达变化。
结果
研究组术后不良反应发生率显著低于对照组（P<0.05）；研究组手术指标恢复情况优于对照组（P<0.05）。治疗后，两组血清sICAM-1和IL-6水平均有一定程度下降，且研究组血清sICAM-1和IL-6炎症因子水平显著低于对照组（P<0.05）。治疗后，两组心理状态、身体健康、独立能力、社会关系、周围环境及个人信念评分均显著高于治疗前（P<0.05）。治疗后，治疗组各领域评分显著高于对照组（P<0.05）。
结论
超声刀联合内给氧辅助硝普钠静脉滴注治疗老年急性胆囊炎患者安全可行，但需把握合适的手术时机并熟练操作。
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