Sorva R, Heiskanen O, Perheentupa J
Children's Hospital, Helsinki University Hospital, Finland.
Childs Nerv Syst. 1988 Apr;4(2):97-9. doi: 10.1007/BF00271387.
Twenty-two children with craniopharyngioma were operated on in our Department of Neurosurgery from 1970 to 1981. Removal was total in 11 patients. There was one surgical death, but no recurrences in this group. Only partial removal could be performed in 10 children, followed by stereotactic radiotherapy in one. Recurrences have occurred in 4 of these children and 2 of them have died. In 1 child a biopsy was performed, followed by insertion of a shunt and stereotactic radiotherapy. Nine years after treatment there have still been no recurrences. Visual acuity was unchanged after the procedure in 17/21 survivors, improved in 1, and deteriorated in 3. The visual fields remained unchanged in 11, improved in 3, and deteriorated in 7. The visual fields and visual acuity were normal postoperatively in 5 patients. Hypopituitarism was more extensive after the procedure. We recommended an attempt at total removal whenever possible.
1970年至1981年期间，我院神经外科对22例颅咽管瘤患儿进行了手术治疗。11例患儿实现了肿瘤全切。该组中有1例手术死亡，但无复发病例。10例患儿仅能进行部分切除，其中1例随后接受了立体定向放射治疗。这些患儿中有4例复发，其中2例死亡。1例患儿进行了活检，随后植入分流管并接受立体定向放射治疗。治疗9年后仍无复发。21例存活患儿中，17例术后视力无变化，1例改善，3例恶化。11例视野无变化，3例改善，7例恶化。5例患者术后视野和视力正常。术后垂体功能减退更为广泛。我们建议尽可能尝试全切肿瘤。
