Laboratory of Host-Pathogen Dynamics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Laboratory of Host-Pathogen Dynamics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Mol Cell. 2021 May 20;81(10):2061-2063. doi: 10.1016/j.molcel.2021.04.025.
Jones et al. (2021) and Zhang et al. (2021) reveal by cryo-EM the oligomeric crown-like structure formed by a membrane-associated Chikungunya virus replication protein that gates the export of newly synthesized viral RNA from viral replication organelles.
琼斯等人(2021 年)和张等人(2021 年)通过冷冻电镜揭示了一种膜相关的基孔肯雅病毒复制蛋白形成的寡聚冠状结构,该结构可以控制新合成的病毒 RNA 从病毒复制细胞器中输出。