因抗利尿激素不适当分泌综合征（SIADH）相关的 COVID-19 导致的电解质失衡引起的有症状窦性心动过缓：一例报告。
Symptomatic sinus bradycardia due to electrolyte imbalances in syndrome of inappropriate antidiuretic hormone (SIADH) related covid-19: a case report.
机构信息
Departement of Cardiology and Vascular Medicine, Hasanuddin University, Makassar, Indonesia.
Dr. Wahidin Sudirohusodo National General Hospital, Makassar, Indonesia.
出版信息
BMC Infect Dis. 2021 May 21;21(1):465. doi: 10.1186/s12879-021-06143-2.
BACKGROUND
Coronavirus Disease-2019 (COVID-19) has been declared a global pandemic since March 11th, 2020. Despite emerging reports and literature covering a broad spectrum of COVID-19 clinical manifestations, facets of COVID-19 have not been fully elucidated. To the authors' concern, sinus bradycardia as a manifestation of COVID-19-induced syndrome of inappropriate antidiuretic hormone (SIADH) has never been reported before.
CASE PRESENTATION
In this paper, we report a case of a 59-year-old male patient with confirmed COVID-19 initially presented with presyncope. Further investigations reveal sinus bradycardia related to COVID-19-induced SIADH. This case highlights the possibility of immuno-neuroendocrino-cardiovascular crosstalk resulting in an atypical manifestation of COVID-19: near syncope due to sinus bradycardia.
CONCLUSIONS
Another possible cause of sinus bradycardia in COVID-19 is electrolyte imbalance due to COVID-19-related SIADH.
背景
自 2020 年 3 月 11 日以来，新型冠状病毒肺炎（COVID-19）已被宣布为全球大流行。尽管有大量报道和文献涵盖了 COVID-19 的广泛临床表现，但 COVID-19 的某些方面仍未得到充分阐明。令作者关注的是，窦性心动过缓作为 COVID-19 引起的抗利尿激素分泌不当综合征（SIADH）的表现以前从未报道过。
病例介绍
本文报告了一例 59 岁男性 COVID-19 患者，最初表现为先兆晕厥。进一步的检查显示窦性心动过缓与 COVID-19 引起的 SIADH 有关。该病例提示了免疫神经内分泌心血管相互作用的可能性，导致 COVID-19 的非典型表现：窦性心动过缓导致近乎晕厥。
结论
COVID-19 中窦性心动过缓的另一个可能原因是 COVID-19 相关 SIADH 引起的电解质失衡。
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