Carcinogenic property of JBO(P) variety of jute batching oil.

The topical application of neat JBO-P variety of jute batching oil (JBO) three times a week has been found to produce skin tumours locally with 13 weeks of treatment on Swiss albino mice. In another set of experiments, 3 times/week topical application of JBO on Swiss albino mouse skin previously initiated (s.c., 1 mg/g body wt.) with urethane resulted in induction of tumours (squamous cell papillomas and keratoacanthomas) in 8 weeks. These results suggest that the JBO-P variety of jute batching oil could be a complete carcinogen or a tumour promoting substance on mouse skin.