性别和 G 蛋白偶联雌激素受体影响血管僵硬。
Sex and the G Protein-Coupled Estrogen Receptor Impact Vascular Stiffness.
机构信息
Department of Pharmacology (B.O.O., C.M.A., N.R.H., K.L.G., S.S.G., I.K.-D., T.J.W., B.V., M.A.Z., S.H.L.), Tulane University, New Orleans, LA.
Department of Biomedical Engineering (G.L.C., D.J.L., C.L.B., K.S.M.), Tulane University, New Orleans, LA.
出版信息
Hypertension. 2021 Jul;78(1):e1-e14. doi: 10.1161/HYPERTENSIONAHA.120.16915. Epub 2021 May 24.
Abstract
[Figure: see text].
摘要
[图：见正文]。
相似文献
1
Sex and the G Protein-Coupled Estrogen Receptor Impact Vascular Stiffness.性别和 G 蛋白偶联雌激素受体影响血管僵硬。
Hypertension. 2021 Jul;78(1):e1-e14. doi: 10.1161/HYPERTENSIONAHA.120.16915. Epub 2021 May 24.
2
Ovariectomy-Induced Arterial Stiffening Differs From Vascular Aging and Is Reversed by GPER Activation.卵巢切除引起的动脉僵硬不同于血管老化，并可通过 GPER 激活逆转。
Hypertension. 2024 May;81(5):e51-e62. doi: 10.1161/HYPERTENSIONAHA.123.22024. Epub 2024 Mar 6.
3
Sex differences in vascular aging and impact of GPER deletion.血管老化的性别差异及 GPER 缺失的影响
Am J Physiol Heart Circ Physiol. 2022 Aug 1;323(2):H336-H349. doi: 10.1152/ajpheart.00238.2022. Epub 2022 Jun 24.
4
Carotid-Femoral Pulse Transit Time Variability Predicted Mortality and Improved Risk Stratification in the Elderly.颈-股脉搏波传导时间可变性预测老年人的死亡率和改善风险分层。
Hypertension. 2021 Nov;78(5):1287-1295. doi: 10.1161/HYPERTENSIONAHA.121.17891. Epub 2021 Sep 27.
5
Impaired Central Pulsatile Hemodynamics in Children and Adolescents With Marfan Syndrome.马凡综合征患儿和青少年的中枢脉动血流动力学受损。
J Am Heart Assoc. 2017 Nov 7;6(11):e006815. doi: 10.1161/JAHA.117.006815.
6
Intrauterine growth restriction influences vascular remodeling and stiffening in the weanling rat more than sex or diet.宫内生长受限对断奶大鼠血管重塑和硬化的影响比性别或饮食的影响更大。
Am J Physiol Heart Circ Physiol. 2017 Feb 1;312(2):H250-H264. doi: 10.1152/ajpheart.00610.2016. Epub 2016 Nov 23.
7
Arterial Stiffness Assessment by Shear Wave Elastography and Ultrafast Pulse Wave Imaging: Comparison with Reference Techniques in Normotensives and Hypertensives.剪切波弹性成像和超快脉搏波成像评估动脉僵硬度：与正常血压者和高血压者的参考技术比较。
Ultrasound Med Biol. 2019 Mar;45(3):758-772. doi: 10.1016/j.ultrasmedbio.2018.10.032. Epub 2019 Jan 12.
8
Relations of Arterial Stiffness With Postural Change in Mean Arterial Pressure in Middle-Aged Adults: The Framingham Heart Study.中年成年人动脉僵硬度与平均动脉压体位变化的关系：弗雷明汉心脏研究
Hypertension. 2017 Apr;69(4):685-690. doi: 10.1161/HYPERTENSIONAHA.116.08116.
9
Blood Pressure Variability, Arterial Stiffness, and Arterial Remodeling.血压变异性、动脉僵硬度和动脉重构。
Hypertension. 2018 Oct;72(4):1002-1010. doi: 10.1161/HYPERTENSIONAHA.118.11325.
10
G protein-coupled estrogen receptor inhibits vascular prostanoid production and activity.G蛋白偶联雌激素受体抑制血管前列腺素的产生和活性。
J Endocrinol. 2015 Oct;227(1):61-9. doi: 10.1530/JOE-15-0257. Epub 2015 Aug 24.
引用本文的文献
1
ACE trial design: Equol targeting estrogen receptor-β in vascular and cognitive aging.ACE试验设计：雌马酚靶向血管和认知衰老中的雌激素受体-β。
Alzheimers Dement (N Y). 2025 Aug 18;11(3):e70144. doi: 10.1002/trc2.70144. eCollection 2025 Jul-Sep.
2
The impact of androgens on cardiovascular control mechanisms in polycystic ovary syndrome: Recent advances and translational approaches.雄激素对多囊卵巢综合征心血管控制机制的影响：最新进展与转化方法
J Physiol. 2025 May;603(10):2937-2957. doi: 10.1113/JP287288. Epub 2025 May 5.
3
Sexual dimorphism in the downregulation of extracellular matrix genes contributes to aortic stiffness in female mice.细胞外基质基因下调中的性别二态性导致雌性小鼠主动脉僵硬。
Am J Physiol Heart Circ Physiol. 2025 Mar 1;328(3):H472-H483. doi: 10.1152/ajpheart.00432.2024. Epub 2025 Jan 28.
4
Sex-specific cardiovascular adaptations to simulated microgravity in Sprague-Dawley rats.性特异性心血管对Sprague-Dawley大鼠模拟微重力的适应性变化
NPJ Microgravity. 2024 Dec 19;10(1):110. doi: 10.1038/s41526-024-00450-z.
5
Hypertension disrupts the vascular clock in both sexes.高血压会破坏男性和女性的血管生物钟。
Am J Physiol Heart Circ Physiol. 2024 Oct 1;327(4):H765-H777. doi: 10.1152/ajpheart.00131.2024. Epub 2024 Jul 26.
6
Testosterone deficiency promotes arterial stiffening independent of sex chromosome complement.睾酮缺乏症会导致动脉僵硬，而与性染色体组成无关。
Biol Sex Differ. 2024 Jun 6;15(1):46. doi: 10.1186/s13293-024-00624-0.
7
Ovariectomy-Induced Arterial Stiffening Differs From Vascular Aging and Is Reversed by GPER Activation.卵巢切除引起的动脉僵硬不同于血管老化，并可通过 GPER 激活逆转。
Hypertension. 2024 May;81(5):e51-e62. doi: 10.1161/HYPERTENSIONAHA.123.22024. Epub 2024 Mar 6.
8
Dihydrotestosterone induces arterial stiffening in female mice.双氢睾酮可导致雌性小鼠动脉僵硬度增加。
Biol Sex Differ. 2024 Jan 23;15(1):9. doi: 10.1186/s13293-024-00586-3.
9
Effects of dietary soy content on cerebral artery function and behavior in ovariectomized female mice.饮食中大豆含量对去卵巢雌性小鼠大脑动脉功能和行为的影响。
Am J Physiol Heart Circ Physiol. 2024 Mar 1;326(3):H636-H647. doi: 10.1152/ajpheart.00618.2023. Epub 2023 Dec 29.
10
Testosterone Deficiency Promotes Arterial Stiffening Independent of Sex Chromosome Complement.睾酮缺乏促进动脉僵硬度增加，与性染色体组成无关。
Res Sq. 2023 Oct 14:rs.3.rs-3370040. doi: 10.21203/rs.3.rs-3370040/v1.
本文引用的文献
1
Reduced stiffness and augmented traction force in type 2 diabetic coronary microvascular smooth muscle.2 型糖尿病患者冠状动脉微血管平滑肌僵硬度降低和牵引力增强。
Am J Physiol Heart Circ Physiol. 2020 Jun 1;318(6):H1410-H1419. doi: 10.1152/ajpheart.00542.2019. Epub 2020 May 1.
2
Arterial Stiffness Accelerates Within 1 Year of the Final Menstrual Period: The SWAN Heart Study.绝经后 1 年内动脉僵硬度加速：SWAN 心脏研究。
Arterioscler Thromb Vasc Biol. 2020 Apr;40(4):1001-1008. doi: 10.1161/ATVBAHA.119.313622. Epub 2020 Jan 23.
3
PM-induced inflammation and lipidome alteration associated with the development of atherosclerosis based on a targeted lipidomic analysis.基于靶向脂质组学分析的 PM 诱导的炎症和脂质组改变与动脉粥样硬化的发展相关。
Environ Int. 2020 Mar;136:105444. doi: 10.1016/j.envint.2019.105444. Epub 2020 Jan 11.
4
Exercise and Arterial Stiffness in the Elderly: A Combined Cross-Sectional and Randomized Controlled Trial (EXAMIN AGE).老年人运动与动脉僵硬度：一项横断面研究与随机对照试验相结合的研究（EXAMIN AGE）
Front Physiol. 2019 Sep 4;10:1119. doi: 10.3389/fphys.2019.01119. eCollection 2019.
5
G Protein-Coupled Estrogen Receptor Protects From Angiotensin II-Induced Increases in Pulse Pressure and Oxidative Stress.G蛋白偶联雌激素受体可保护机体免受血管紧张素II诱导的脉压升高和氧化应激的影响。
Front Endocrinol (Lausanne). 2019 Aug 27;10:586. doi: 10.3389/fendo.2019.00586. eCollection 2019.
6
Interrelations Between Arterial Stiffness, Target Organ Damage, and Cardiovascular Disease Outcomes.动脉僵硬度、靶器官损伤与心血管疾病结局的相互关系。
J Am Heart Assoc. 2019 Jul 16;8(14):e012141. doi: 10.1161/JAHA.119.012141. Epub 2019 Jul 13.
7
Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association.《2019年心脏病和中风统计数据更新：美国心脏协会报告》
Circulation. 2019 Mar 5;139(10):e56-e528. doi: 10.1161/CIR.0000000000000659.
8
Maladaptive aortic remodeling in hypertension associates with dysfunctional smooth muscle contractility.高血压患者的主动脉重构不良与平滑肌收缩功能障碍有关。
Am J Physiol Heart Circ Physiol. 2019 Feb 1;316(2):H265-H278. doi: 10.1152/ajpheart.00503.2017. Epub 2018 Nov 9.
9
Interaction Between Hypertension and Arterial Stiffness.高血压与动脉僵硬度之间的相互作用
Hypertension. 2018 Oct;72(4):796-805. doi: 10.1161/HYPERTENSIONAHA.118.11212.
10
New insights into arterial stiffening: does sex matter?动脉僵硬度的新见解：性别重要吗？
Am J Physiol Heart Circ Physiol. 2018 Nov 1;315(5):H1073-H1087. doi: 10.1152/ajpheart.00132.2018. Epub 2018 Jul 20.
Zotero 插件