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与 PEG 相关的纵向并发症:初次 PEG 置入后患者在 30 天和 1 年内经历的并发症的发生率和严重程度。

Longitudinal complications associated with PEG: Rate and severity of 30-day and 1-year complications experienced by patients after primary PEG insertion.

机构信息

University of Birmingham, College of Medical and Dental Sciences, United Kingdom.

Royal Wolverhampton NHS Trust, United Kingdom.

出版信息

Clin Nutr ESPEN. 2021 Jun;43:514-521. doi: 10.1016/j.clnesp.2021.02.004. Epub 2021 Feb 24.

Abstract

BACKGROUND AND AIMS

Percutaneous Endoscopic Gastrostomy (PEG) feeding is utilised in patients with exceptionally poor oral intake but is associated with both short and long-term complications. This study reviews longitudinal PEG complications and compares key subgroups.

METHODS

Single-centre retrospective observational study of all patients receiving PEG insertion between January 2016 and December 2018.

RESULTS

306 patients met the inclusion criteria. The mean age at insertion was 67 years. The majority were cared for in their own home (80.4%) by themselves or family (74.9%). 127 PEG tubes were inserted for dysphagia and 165 prophylactically prior to treatment for head and neck cancer. In the first 30 days 16.7% experienced a complication. The most frequently reported was peristomal pain (9.2%). In the first year, 35.6% experienced at least one complication, 12.4% two complications and 6.6% three complications and 6.5% required inpatient treatment for their complication. The most common was pain (14.4%) followed by site weeping, site infection and external overgranulation. Patients with dysphagia took longer to develop complications, had fewer complications and took longer to require management by members of the secondary care team than those with head and neck cancer. Discounting peristomal pain, there was no difference in total complications between patients caring for themselves when compared to those receiving professional input.

CONCLUSION

One third of patients will experience a complication related to their PEG tube over 1 year, but the majority are managed in an outpatient setting. This study has implications for planning support services and consenting and counselling patients pre-PEG-insertion.

摘要

背景和目的

经皮内镜下胃造口术(PEG)用于摄入极差的患者,但与短期和长期并发症相关。本研究回顾性分析了长期 PEG 并发症,并比较了关键亚组。

方法

对 2016 年 1 月至 2018 年 12 月期间所有接受 PEG 置入的患者进行单中心回顾性观察研究。

结果

306 例患者符合纳入标准。置管时的平均年龄为 67 岁。大多数患者(80.4%)在家中由自己或家人(74.9%)照顾。127 例 PEG 管因吞咽困难而插入,165 例预防性插入用于头颈部癌症治疗。在 30 天内,16.7%的患者出现并发症。最常见的是造口周围疼痛(9.2%)。在第一年,35.6%的患者至少发生了一次并发症,12.4%的患者发生了两次并发症,6.6%的患者发生了三次并发症,6.5%的患者因并发症需要住院治疗。最常见的是疼痛(14.4%),其次是造口部位渗出、感染和外源性过度生长。与头颈部癌症患者相比,有吞咽困难的患者发生并发症的时间更长,并发症更少,需要二级保健团队成员管理的时间也更长。不包括造口周围疼痛,自理患者与接受专业护理患者的总并发症发生率无差异。

结论

三分之一的患者在 1 年内会出现与 PEG 管相关的并发症,但大多数并发症在门诊即可得到管理。这项研究对规划支持服务以及在 PEG 置入前对患者进行同意和咨询具有重要意义。

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