Meng Jingjing, Tang Chulei, Xiao Xueling, Välimäki Maritta, Wang Honghong
Xiangya Nursing School of Central South University, Changsha, China.
Department of Nursing Science, University of Turku, Turku, Finland.
Front Psychol. 2021 May 5;12:666766. doi: 10.3389/fpsyg.2021.666766. eCollection 2021.
: The comorbidity of posttraumatic stress disorder (PTSD) and depression is common among people living with the HIV (PLWH). Given the high prevalence and serious clinical consequences of the comorbidity of these two disorders, we conducted a latent profile analysis to examine the co-occurrence pattern of PTSD and depression in PLWH. : The data for this cross-sectional study of PLWH were collected from 602 patients with HIV in China. A secondary analysis using latent profile analysis was conducted to examine HIV-related PTSD and depression symptoms. A four-class solution fits the data best, with the four classes characterized as asymptomatic (42.9%), mild symptoms (33.9%), low to moderate symptoms (19.8%), and high to moderate symptoms (3.4%). The severity of PTSD and depression symptoms was comparable in this solution, and no group was dominated by PTSD or depression. : The absence of a distinct subcluster of PLWH with only PTSD or depression symptoms supports that PTSD and depression in PLWH are psychopathological manifestations after traumatic exposures. Health care staff should pay more attention to the existence of comorbid symptoms of individuals, develop integrated interventions for the symptoms cluster, and evaluate their effectiveness in clinical practice.
创伤后应激障碍（PTSD）与抑郁症的共病现象在艾滋病毒感染者（PLWH）中很常见。鉴于这两种疾病共病的高患病率及严重的临床后果，我们进行了潜在类别分析，以研究PLWH中PTSD和抑郁症的共现模式。
这项针对PLWH的横断面研究数据来自中国602名艾滋病毒患者。采用潜在类别分析进行二次分析，以研究与艾滋病毒相关的PTSD和抑郁症状。四类解决方案最符合数据，这四类分别为无症状（42.9%）、轻度症状（33.9%）、低至中度症状（19.8%）和高至中度症状（3.4%）。在此解决方案中，PTSD和抑郁症状的严重程度相当，且没有一组以PTSD或抑郁症为主导。
不存在仅患有PTSD或抑郁症症状的PLWH独特亚组，这支持了PLWH中的PTSD和抑郁症是创伤暴露后的精神病理表现。医护人员应更加关注个体共病症状的存在，针对症状群制定综合干预措施，并在临床实践中评估其有效性。
