Department of Health Services Management, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran.
Student Research Committee, School of Nursing and Midwifery, Iran University of Medical Sciences, Tehran, Iran.
BMJ Support Palliat Care. 2019 Dec;9(4):404-412. doi: 10.1136/bmjspcare-2019-001952. Epub 2019 Sep 19.
The incidence of some fatal diseases, including HIV/AIDS, accompanied by depression has become a significant concern in developed, developing and underdeveloped countries. A great deal of time and money are spent on controlling and reducing the complications of this infection across the world. Accordingly, the main purpose of this study was to clarify the global prevalence rate of depression in patients living with HIV/AIDS via a systematic review and meta-analysis.
All articles in English, published between 2000 and 2018, were systematically searched from the original databases of Web of Science, PubMed, Scopus, Cochrane Library, Google Scholar and Embase. As a result, a total of 118 articles were identified.
The total sample size in these articles was 51143 people, and the number of patients suffering from moderate and severe levels of depression was 14 942. The results of the analysis based on the random-effects (DerSimonian and Laird) model revealed that the prevalence rate of depression in patients with HIV/AIDS was 31% (95% CI 28% to 34%), with a 98% heterogeneity index which was reported significant. Meanwhile, the highest prevalence rate of depression based on continent was in South America at 44% (95% CI 35% to 53%) and the lowest rate was in Europe at 22% (95% CI 17% to 27%).
In general, there was a higher prevalence rate of depression in developing and underdeveloped countries than in developed countries, which could be attributed to the advancement of science and the possibilities for early diagnosis of this syndrome.
CRD42019119137.
在发达国家、发展中国家和欠发达国家，一些致命疾病（包括艾滋病毒/艾滋病）发病率伴随抑郁的出现，已成为一个重大问题。全世界投入了大量的时间和资金来控制和减少这种感染的并发症。因此，本研究的主要目的是通过系统评价和荟萃分析明确艾滋病毒/艾滋病患者中抑郁的全球流行率。
从 Web of Science、PubMed、Scopus、Cochrane Library、Google Scholar 和 Embase 的原始数据库中系统地搜索了 2000 年至 2018 年期间发表的所有英文文章。结果共确定了 118 篇文章。
这些文章的总样本量为 51143 人，患有中重度抑郁的患者人数为 14942 人。基于随机效应（DerSimonian 和 Laird）模型的分析结果显示，艾滋病毒/艾滋病患者的抑郁发生率为 31%（95%CI 28%至 34%），报告的异质性指数为 98%，具有统计学意义。同时，基于大陆的抑郁发生率最高的是南美洲，为 44%（95%CI 35%至 53%），最低的是欧洲，为 22%（95%CI 17%至 27%）。
总的来说，发展中国家和欠发达国家的抑郁发生率高于发达国家，这可能归因于科学的进步和这种综合征的早期诊断的可能性。
CRD42019119137。
