• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

自发性脾破裂:急性髓系白血病的一种罕见并发症。病例报告。

Spontaneous splenic rupture: A rare complication of acute myeloid leukemia. Report of a case.

作者信息

Hajri Amal, Yaqine Karim, El Massi Salaheddine, Errguibi Driss, Boufettal Rachid, El Jai Saad Rifki, Chehab Farid

机构信息

Departement of General Surgery, University Hospital Centre Ibn Rochd, Casablanca, Morocco.

Faculty of Medecine and Pharmacy, Hassan II University, Casablanca, Morocco.

出版信息

Ann Med Surg (Lond). 2021 May 5;65:102286. doi: 10.1016/j.amsu.2021.102286. eCollection 2021 May.

DOI:10.1016/j.amsu.2021.102286
PMID:34026095
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8121875/
Abstract

INTRODUCTION

Spontaneous rupture of the spleen (SPR) is a rare and severe affection, difficult to diagnose, with multiple causes such as: Infectious and hematologic affections which represent more than half of the cases. Among this subset of patients, acute myeloid leukemia is one of the causes.

PRESENTATION OF CASE

A 48-year-old man undergoing chemotherapy for acute myeloid leukemia presented with acute intense abdominal pain. Computed tomography showed Abdominal CT scan showed a splenic rupture with abundant hemoperitoneum and bilateral pleural effusion. The patient presented hemodynamic instability and was immediately operated, splenectomy were performed.

DISCUSSION

Spontaneous rupture of the spleen usually presents as a severe abdominal syndrome, which may accompany non-specific symptoms.Two signs are suggestive of splenic rupture: Kehr's sign (left diaphragmatic irritation resulting in referred pain to the left shoulder) and Balance's sign (palpable tender mass in the left upper quadrant. Diagnostic methods of choice are computed tomography andultrasound. The prognosis is depending on the quality of care and the nature of the etiology. Splenectomy remains the cornerstone of the treatment of splenic rupture. It is important to include splenic rupture as a differential diagnosis for acute abdominal pain, especially in patients with hematologic malignancy, since early recognition and treatment increase patient survival and improve the prognosis.

CONCLUSION

Even if spontaneous splenic rupture is rare, every clinician should have in mind the reflex to think of it, especially in patients with hematologic malignancies.

摘要

引言

自发性脾破裂(SPR)是一种罕见且严重的病症,难以诊断,病因多样,如:感染性和血液学病症,这些病因占病例的一半以上。在这类患者中,急性髓系白血病是病因之一。

病例介绍

一名48岁因急性髓系白血病接受化疗的男性患者出现急性剧烈腹痛。计算机断层扫描显示腹部CT扫描显示脾破裂伴大量腹腔积血和双侧胸腔积液。患者出现血流动力学不稳定,立即接受手术,进行了脾切除术。

讨论

自发性脾破裂通常表现为严重的腹部综合征,可能伴有非特异性症状。有两个体征提示脾破裂:凯尔氏征(左膈刺激导致左肩牵涉痛)和巴伦斯征(左上象限可触及压痛肿块)。首选的诊断方法是计算机断层扫描和超声检查。预后取决于护理质量和病因性质。脾切除术仍然是脾破裂治疗的基石。将脾破裂作为急性腹痛的鉴别诊断很重要,尤其是在血液系统恶性肿瘤患者中,因为早期识别和治疗可提高患者生存率并改善预后。

结论

即使自发性脾破裂很少见,但每位临床医生都应牢记考虑到这种情况,尤其是在血液系统恶性肿瘤患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aea3/8121875/ee5460aa755e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aea3/8121875/c59643c0e496/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aea3/8121875/ee5460aa755e/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aea3/8121875/c59643c0e496/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aea3/8121875/ee5460aa755e/gr2.jpg

相似文献

1
Spontaneous splenic rupture: A rare complication of acute myeloid leukemia. Report of a case.自发性脾破裂:急性髓系白血病的一种罕见并发症。病例报告。
Ann Med Surg (Lond). 2021 May 5;65:102286. doi: 10.1016/j.amsu.2021.102286. eCollection 2021 May.
2
Spontaneous splenic rupture in a patient with chronic myeloid leukemia: A case report.慢性粒细胞白血病患者自发性脾破裂:一例报告
Int J Surg Case Rep. 2020;66:122-125. doi: 10.1016/j.ijscr.2019.11.051. Epub 2019 Nov 30.
3
Delayed Splenic Rupture due to an Occult Primary Injury.隐匿性原发损伤致迟发性脾破裂
J Coll Physicians Surg Pak. 2022 Jul;32(7):931-933. doi: 10.29271/jcpsp.2022.07.931.
4
[Occult rupture of the spleen in a patient with infectious mononucleosis].[传染性单核细胞增多症患者的隐匿性脾破裂]
G Chir. 2010 Mar;31(3):86-90.
5
Spontaneous splenic rupture due to Peliosis and the association with malignancy: A case series and literature review.由紫癜引起的自发性脾破裂及其与恶性肿瘤的关联:病例系列及文献综述
Int J Surg Case Rep. 2023 Sep;110:108676. doi: 10.1016/j.ijscr.2023.108676. Epub 2023 Aug 19.
6
Large B-cell lymphoma presenting as acute abdominal pain and spontaneous splenic rupture; a case report and review of relevant literature.以急性腹痛和自发性脾破裂为表现的大B细胞淋巴瘤:一例报告及相关文献复习
World J Emerg Surg. 2006 Nov 28;1:35. doi: 10.1186/1749-7922-1-35.
7
Epstein-Barr Virus-Associated Atraumatic Spleen Laceration Presenting with Neck and Shoulder Pain.表现为颈部和肩部疼痛的爱泼斯坦-巴尔病毒相关非创伤性脾破裂
Am J Case Rep. 2015 Oct 30;16:774-7. doi: 10.12659/ajcr.893919.
8
[Spontaneous rupture of the spleen in infectious mononucleosis: case report and review of the literature].[传染性单核细胞增多症中脾脏自发性破裂:病例报告及文献复习]
Acta Med Croatica. 2003;57(2):141-3.
9
Chronic lymphocytic leukemia, a rare cause of spontaneous rupture of the spleen.慢性淋巴细胞白血病是脾脏自发性破裂的罕见原因。
Int J Surg Case Rep. 2022 Jul;96:107315. doi: 10.1016/j.ijscr.2022.107315. Epub 2022 Jun 16.
10
A case of pathologic splenic rupture as the initial manifestation of acute myeloid leukemia M2.以病理性脾破裂为首发表现的急性髓系白血病 M2 一例。
Yonsei Med J. 2010 Jan;51(1):138-40. doi: 10.3349/ymj.2010.51.1.138. Epub 2009 Dec 29.

本文引用的文献

1
The SCARE 2020 Guideline: Updating Consensus Surgical CAse REport (SCARE) Guidelines.SCARE 2020 指南:更新共识手术病例报告(SCARE)指南。
Int J Surg. 2020 Dec;84:226-230. doi: 10.1016/j.ijsu.2020.10.034. Epub 2020 Nov 9.
2
Spontaneous Splenic Rupture Complicating Severe Infection: A Case Report and Literature Review.自发性脾破裂并发严重感染:一例报告及文献复习
Case Rep Infect Dis. 2019 Oct 24;2019:2781647. doi: 10.1155/2019/2781647. eCollection 2019.
3
Spontaneous Splenic Rupture as a Rare Initial Presentation in an Acute Lymphoblastic Leukemia Patient.
自发性脾破裂作为急性淋巴细胞白血病患者罕见的首发表现。
Diagnostics (Basel). 2019 Oct 18;9(4):152. doi: 10.3390/diagnostics9040152.
4
Three cases of spontaneous splenic rupture in malignant lymphoma.恶性淋巴瘤自发性脾破裂三例。
Int J Hematol. 2018 Dec;108(6):647-651. doi: 10.1007/s12185-018-2523-2. Epub 2018 Aug 24.
5
Identification and management of nontraumatic splenic rupture.非创伤性脾破裂的识别与处理
J Perioper Pract. 2017 Dec;27(12):296-297. doi: 10.1177/175045891702701202.
6
Spontaneous splenic rupture in an acute leukemia patient with splenic tuberculosis: A case report.一名急性白血病合并脾结核患者的自发性脾破裂:病例报告
Mol Clin Oncol. 2017 Feb;6(2):209-213. doi: 10.3892/mco.2016.1120. Epub 2016 Dec 28.
7
Systematic review of atraumatic splenic rupture.非创伤性脾破裂的系统评价
Br J Surg. 2009 Oct;96(10):1114-21. doi: 10.1002/bjs.6737.
8
Spontaneous splenic rupture precipitated by cough: a case report and a review of the literature.咳嗽诱发的自发性脾破裂:一例报告并文献复习
Scand J Gastroenterol. 2008;43(5):634-7. doi: 10.1080/00365520701763472.
9
Nonoperative management of spontaneous splenic rupture in infectious mononucleosis: a case report and review of the literature.传染性单核细胞增多症自发性脾破裂的非手术治疗:一例报告并文献复习
Pediatrics. 2007 Aug;120(2):e432-5. doi: 10.1542/peds.2006-3071.
10
Large B-cell lymphoma presenting as acute abdominal pain and spontaneous splenic rupture; a case report and review of relevant literature.以急性腹痛和自发性脾破裂为表现的大B细胞淋巴瘤:一例报告及相关文献复习
World J Emerg Surg. 2006 Nov 28;1:35. doi: 10.1186/1749-7922-1-35.