Department of Internal Medicine, Dong-A University College of Medicine, Seo-gu, Busan, Korea.
Yonsei Med J. 2010 Jan;51(1):138-40. doi: 10.3349/ymj.2010.51.1.138. Epub 2009 Dec 29.
A pathologic splenic rupture refers to a rupture without trauma. A splenic rupture as the initial manifestation of acute myeloid leukemia is extremely rare. In this study, we described a rare case of acute myeloid leukemia presenting principally as an acute abdomen due to a pathologic splenic rupture in a 35-year old male patient. We can assert that a pathologic splenic rupture in hematologic diseases is a potentially life-threatening complication, which necessitates immediate operative intervention. Any such patient complaining about left upper abdominal tenderness should be closely observed, and further diagnostic investigations (ultrasonograph of the abdomen, abdominal CT scan) should be initiated in order to rule out a splenic rupture. The oncologist should be aware of this rare initial presentation of acute myeloid leukemia (AML) M2, as the condition generally necessitates a prompt splenectomy.
病理性脾破裂是指无外伤的脾破裂。以脾破裂为首发表现的急性髓系白血病极为罕见。本研究描述了 1 例罕见的 35 岁男性病例，主要表现为急性腹痛，其原因为病理性脾破裂。我们可以断言，血液系统疾病中的病理性脾破裂是一种潜在的危及生命的并发症，需要立即进行手术干预。任何有左上腹压痛的此类患者都应密切观察，并进一步进行诊断性检查（腹部超声、腹部 CT 扫描）以排除脾破裂。肿瘤学家应该意识到这种急性髓系白血病（AML）M2 的罕见首发表现，因为这种情况通常需要迅速进行脾切除术。
