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孕晚期母体血清地高辛和氟卡尼浓度的变化——胎儿水肿型室上性心动过速病例报告

Transition of maternal serum concentration of digoxin and flecainide in the third trimester-A case report of fetal supraventricular tachycardia with hydrops.

作者信息

Takatsuka Hirokazu, Wakabayashi Kayo, Yamazaki Shingo, Tanaka Hirokazu, Omoto Akiko, Suzuki Takaaki, Shozu Makio, Ishii Itsuko

机构信息

Division of Pharmacy Chiba University Hospital Chiba Japan.

Department of Obstetrics and Gynecology International University of Health and Welfare Narita Hospital Chiba Japan.

出版信息

Clin Case Rep. 2021 Mar 27;9(5):e03992. doi: 10.1002/ccr3.3992. eCollection 2021 May.

Abstract

When transplacental therapy is conducted, the maternal serum concentrations of digoxin and flecainide may fluctuate throughout third trimester. Therefore, TDM may be effective in improving the efficacy and safety of treatment.

摘要

进行经胎盘治疗时,地高辛和氟卡尼的母体血清浓度在整个孕晚期可能会波动。因此,治疗药物监测可能有助于提高治疗的有效性和安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/014c/8117821/9108ee311e3e/CCR3-9-e03992-g002.jpg

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