全膝关节置换术后“自发性”肝素诱导的血小板减少症和血栓形成：2例报告
"Spontaneous" Heparin-Induced Thrombocytopenia and Thrombosis After Total Knee Arthroplasty: A Report of 2 Cases.
作者信息
Olevsky Olga M, Rosove Michael H
机构信息
Division of Hematology-Oncology, UCLA Department of Medicine, David Geffen School of Medicine, Los Angeles, CA, USA.
出版信息
Arthroplast Today. 2021 May 6;9:50-52. doi: 10.1016/j.artd.2021.03.005. eCollection 2021 Jun.
Abstract
"Spontaneous" heparin-induced thrombocytopenia is a rare and virulent form of heparin-induced thrombocytopenia that occurs in the absence of exposure to any drug of the heparin class of anticoagulants. Most reported cases have occurred after knee replacement surgery. Herein we report 2 additional cases following total knee replacement. Clinical suspicion and immediate initiation of appropriate nonheparin anticoagulation are essential to avoid potentially devastating thrombotic complications.
摘要
“自发性”肝素诱导的血小板减少症是肝素诱导的血小板减少症的一种罕见且严重的形式，它在未接触任何肝素类抗凝药物的情况下发生。大多数报道的病例发生在膝关节置换手术后。在此，我们报告全膝关节置换术后另外2例病例。临床怀疑并立即开始适当的非肝素抗凝对于避免潜在的严重血栓并发症至关重要。
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