Division of Hematology, Oncology, Neuro-Oncology & Stem Cell Transplantation, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Division of Pediatric Surgery and Fertility & Hormone Preservation & Restoration Program, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Pediatr Hematol Oncol. 2022 Feb;39(1):68-73. doi: 10.1080/08880018.2021.1928348. Epub 2021 May 24.
Infertility secondary to chemotherapy, myeloablative conditioning regimens prior to stem cell transplantation, radiation therapy, and/or surgery is an important cause of morbidity and psychosocial distress among pediatric cancer patients. Known options exist for fertility preservation; however, knowledge among providers varies. We conducted a pilot study with an educational intervention over one-hour for hematology-oncology faculty, fellows, and advanced practice providers. Participants completed pre-/post-test assessment on fertility preservation knowledge. Participants' pretest mean (SD) score was 53% (17%), which significantly increased to 72% (11%) in the post-test ( = 0.0004). We demonstrated that a fertility education intervention could improve knowledge regarding infertility risk assessment and fertility preservation options.
化疗引起的不孕、干细胞移植前的骨髓清除性调理方案、放疗和/或手术是导致儿科癌症患者发病率和心理困扰的重要原因。现已有生育力保存的已知选择,但提供者的知识各不相同。我们对血液学-肿瘤学教师、研究员和高级执业护士进行了一项持续一个小时的教育干预的试点研究。参与者在生育力保存知识方面完成了预/后测试评估。参与者的预测试平均(SD)得分为 53%(17%),在后测中显著增加到 72%(11%)(=0.0004)。我们证明,生育力教育干预可以提高对不孕风险评估和生育力保存选择的知识。