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类鼻疽误诊为肺结核 1 例。

Case of melioidosis misdiagnosed as pulmonary tuberculosis.

机构信息

Pulmonary Medicine, St John's National Academy of Health Sciences, Bangalore, Karnataka, India

Pulmonary Medicine, St John's National Academy of Health Sciences, Bangalore, Karnataka, India.

出版信息

BMJ Case Rep. 2021 May 24;14(5):e242499. doi: 10.1136/bcr-2021-242499.

DOI:10.1136/bcr-2021-242499
PMID:34031092
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8154943/
Abstract

Melioidosis is an endemic infection caused by predominantly reported in the coastal parts of India. A 19-year-old male student with no comorbidities presented with features suggestive of pneumonia. He was initiated on antitubercular treatment empirically elsewhere. However, due to lack of response to therapy diagnosis was revisited. Microbiological investigations were unyielding initially. Despite antitubercular treatment, he presented with complications of pneumonia and was diagnosed to have melioidosis. He was initiated on appropriate antibiotics for the intensive and eradication phase. Obtaining microbiological confirmation is of utmost importance to prevent misdiagnosis and undue morbidity and mortality due to these uncommon infections.

摘要

类鼻疽是一种地方性感染病,主要发生在印度沿海地区。一名 19 岁的男性学生,无合并症,表现出肺炎的特征。他曾在其他地方接受过经验性抗结核治疗。然而,由于治疗反应不佳,重新考虑了诊断。最初,微生物学检查没有结果。尽管进行了抗结核治疗,他还是出现了肺炎并发症,并被诊断为类鼻疽。他开始接受强化和清除阶段的适当抗生素治疗。获得微生物学确证非常重要,可避免因这些罕见感染而误诊和不必要的发病率和死亡率。

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本文引用的文献

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2020 Review and revision of the 2015 Darwin melioidosis treatment guideline; paradigm drift not shift.2020 年对 2015 年达尔文类鼻疽病治疗指南的回顾和修订;只是范式漂移,并非转移。
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PLoS Negl Trop Dis. 2013;7(2):e2072. doi: 10.1371/journal.pntd.0002072. Epub 2013 Feb 21.
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The epidemiology and clinical spectrum of melioidosis: 540 cases from the 20 year Darwin prospective study.类鼻疽病的流行病学和临床谱:来自达尔文前瞻性研究 20 年的 540 例病例。
PLoS Negl Trop Dis. 2010 Nov 30;4(11):e900. doi: 10.1371/journal.pntd.0000900.
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Melioidosis: advances in diagnosis and treatment.类鼻疽病:诊断和治疗的新进展。
Curr Opin Infect Dis. 2010 Dec;23(6):554-9. doi: 10.1097/QCO.0b013e32833fb88c.