School of Veterinary Medicine, Kitasato University, Towada 034-8628, Japan.
School of Veterinary Medicine, Kitasato University, Towada 034-8628, Japan.
Meat Sci. 2021 Oct;180:108561. doi: 10.1016/j.meatsci.2021.108561. Epub 2021 May 20.
Bioactive peptides are released from meat proteins by enzymatic hydrolysis (i.e., gastrointestinal digestion, aging/storage, fermentation, and protease treatment). Such peptides attribute physiological functions to meat and meat products and are promising food ingredients for developing functional foods. Meat by-products (e.g., blood and collagen) are also good sources for generating bioactive peptides, since they are produced in large quantities and are rich in proteins. Although protein-derived bioactive peptides are attractive ingredients, their changes by the Maillard reaction during processing, cooking, and storage should be investigated. This article briefly reviews the production of bioactive peptides from meat and meat by-products. Such diverse peptides affects circulatory, nervous, alimentary, and immune systems. Then, the bioactivities of Maillard reaction products (MRPs) generated from protein hydrolysates are discussed. Special attention is paid to bioactivities of 2,5-dimethyl-4-hydroxy-3(2H)-furanone (DMHF) inhalation. As such activities, we have evaluated the impact of DMHF on blood pressure, moods, brainwaves, and dietary intake. Our efforts for understanding various aspects and implication of peptides and MRPs from meat proteins would open new avenues in the meat and food industry.
生物活性肽可通过酶解(即胃肠道消化、老化/储存、发酵和蛋白酶处理)从肉蛋白中释放出来。这些肽赋予肉类和肉类产品生理功能,是开发功能性食品的有前途的食品成分。肉类副产品(如血液和胶原蛋白)也是生成生物活性肽的良好来源,因为它们的产量很大,而且富含蛋白质。尽管蛋白质衍生的生物活性肽是很有吸引力的成分,但在加工、烹饪和储存过程中,它们可能会受到美拉德反应的影响,因此应该对此进行研究。本文简要回顾了从肉类和肉类副产品中生产生物活性肽的方法。这些不同的肽会影响循环、神经、消化和免疫系统。然后,讨论了从蛋白质水解物生成的美拉德反应产物(MRP)的生物活性。特别关注 2,5-二甲基-4-羟基-3(2H)-呋喃酮(DMHF)吸入的生物活性。作为此类活性,我们评估了 DMHF 对血压、情绪、脑波和饮食摄入的影响。我们对理解肉蛋白肽和 MRP 的各个方面和影响的努力将为肉类和食品行业开辟新的途径。