Wang Jifan, Zhang Te, Ding Hanlin, Dong Gaochao, Xu Lin, Jiang Feng
Department of Thoracic Surgery, the Affiliated Cancer Hospital of Nanjing Medical University, Jiangsu Cancer Hospital, Jiangsu Institute of Cancer Research; Jiangsu Key Laboratory of Molecular and Translation Cancer Research, Nanjing 210009, China.
Zhongguo Fei Ai Za Zhi. 2021 May 20;24(5):365-371. doi: 10.3779/j.issn.1009-3419.2021.101.12.
Multiple primary lung cancer (MPLC) refers to lung cancer in which two or more primary lesions occurred simultaneously or successively in different parts of the same patient's lungs. The diagnosis interval is 6 months. MPLC is divided into synchronous MPLC (sMPLC) and metachronous MPLC (mMPLC). sMPLC and intrapulmonary metastasis (IM) are different in treatment strategies and prognosis. However, there are many controversies about the distinction between the two in clinical practice. This article summarizes the current main methods of diagnosing MPLC, and focuses on the latest research progress in distinguishing MPLC from IM. It aims to provide a theoretical basis for accurate diagnosis and treatment of patients with multifocal lung cancer. .
多原发性肺癌(MPLC)是指在同一患者肺部的不同部位同时或先后出现两个或更多原发性病灶的肺癌。诊断间隔为6个月。MPLC分为同步性MPLC(sMPLC)和异时性MPLC(mMPLC)。sMPLC与肺内转移(IM)在治疗策略和预后方面有所不同。然而,在临床实践中,关于两者的区分存在许多争议。本文总结了目前诊断MPLC的主要方法,并重点阐述了区分MPLC与IM的最新研究进展。旨在为多灶性肺癌患者的准确诊断和治疗提供理论依据。