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本文引用的文献

1
Improving Medication History at Admission Utilizing Pharmacy Students and Technicians: A Pharmacy-Driven Improvement Initiative.利用药学专业学生和技术人员改善入院时的用药史:一项由药学推动的改进计划。
P T. 2018 Nov;43(11):676-684.
2
The impact of pharmacist-led medication reconciliation during admission at tertiary care hospital.三级护理医院入院期间由药剂师主导的用药核对的影响。
Int J Clin Pharm. 2018 Feb;40(1):196-201. doi: 10.1007/s11096-017-0568-6. Epub 2017 Dec 16.
3
Accuracy of medication histories collected by pharmacy technicians during hospital admission.药剂师在住院期间收集的用药史的准确性。
Res Social Adm Pharm. 2018 Jul;14(7):695-699. doi: 10.1016/j.sapharm.2017.08.005. Epub 2017 Aug 19.
4
Medication Discrepancies at Pediatric Hospital Discharge.儿科医院出院时的用药差异。
Hosp Pediatr. 2015 Aug;5(8):439-45. doi: 10.1542/hpeds.2014-0085.
5
Optimizing anticonvulsant administration for children before anesthesia: a quality improvement project.麻醉前优化儿童抗惊厥药物给药:一项质量改进项目。
Pediatr Neurol. 2014 Nov;51(5):632-40. doi: 10.1016/j.pediatrneurol.2014.07.029. Epub 2014 Jul 30.
6
Effects of a hospitalwide pharmacy practice model change on readmission and return to emergency department rates.全院药房实践模式改变对再入院率和返回急诊科率的影响。
Am J Health Syst Pharm. 2014 Sep 1;71(17):1469-79. doi: 10.2146/ajhp130686.
7
Anticonvulsant medication errors in children with epilepsy during the home-to-hospital transition.癫痫患儿在从家庭到医院过渡期间的抗惊厥药物用药错误。
J Child Neurol. 2013 Mar;28(3):314-20. doi: 10.1177/0883073812446632. Epub 2012 Jun 29.
8
Completeness of information sources used to prepare best possible medication histories for pediatric patients.用于为儿科患者准备尽可能完善的用药史的信息来源的完整性。
Can J Hosp Pharm. 2011 Jan;64(1):10-5. doi: 10.4212/cjhp.v64i1.979.
9
Prevalence and clinical significance of medication discrepancies at pediatric hospital admission.儿科住院患者用药差异的流行率和临床意义。
Acad Pediatr. 2009 Sep-Oct;9(5):360-365.e1. doi: 10.1016/j.acap.2009.04.007. Epub 2009 Jul 28.
10
Work system design for patient safety: the SEIPS model.以患者安全为导向的工作系统设计:SEIPS模型。
Qual Saf Health Care. 2006 Dec;15 Suppl 1(Suppl 1):i50-8. doi: 10.1136/qshc.2005.015842.

癫痫患儿入院时用药差异的风险因素

Medication Discrepancy Risk Factors for Pediatric Patients With Epilepsy at Hospital Admission.

作者信息

Louiselle Katie, Harte Lory, Thompson Charity, Pabst Damon, Calvert Andrea, Patterson Mark E

出版信息

J Pediatr Pharmacol Ther. 2021;26(4):384-394. doi: 10.5863/1551-6776-26.4.384. Epub 2021 May 19.

DOI:10.5863/1551-6776-26.4.384
PMID:34035684
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8139569/
Abstract

BACKGROUND

Children with epilepsy are at increased risk of medication errors due to disease complexity and administration of time-sensitive medication. Errors frequently occur during transitions of care between home and hospital, a time when accuracy of medication history lists is difficult to ascertain. Adverse events likely from medication discrepancies underscore the importance of improving medication reconciliation upon inpatient intake. This quality improvement project was designed to evaluate and optimize the current medication history process in epileptic patients upon hospital admission at a pediatric academic hospital.

METHODS

A retrospective chart review was conducted on 30 patients with epilepsy admitted in during April, July, and October 2018 to identify unintentional medication discrepancies among 6 sources: documented medication history, inpatient orders from the electronic medical record, outpatient clinic notes, inpatient history and admission document, phone message records, and external insurance claims.

RESULTS

A total of 63% percent of patients had at least 1 unintentional medication discrepancy. Most discrepancies occurred with daily maintenance anticonvulsants (63%). The most common types were omission of medication history (31%) and inpatient order omissions (27%). The number of medication histories completed with at least 1 discrepancy varied across pharmacists, nurses, and physicians, yet differences were not statistically significant.

CONCLUSIONS

Our study found a higher incidence of anticonvulsant discrepancies compared with previous studies. This quality improvement initiative identified the absence of a standardized process as the root cause for the high incidence of anticonvulsant discrepancies in pediatric patients with epilepsy at hospital admission.

摘要

背景

由于疾病的复杂性以及需要按时给药,癫痫患儿发生用药错误的风险增加。在家庭与医院之间的护理转接过程中经常出现错误,而在此期间,用药史清单的准确性很难确定。可能因用药差异导致的不良事件凸显了在住院时改进用药核对的重要性。本质量改进项目旨在评估并优化一家儿科教学医院癫痫患者入院时的当前用药史流程。

方法

对2018年4月、7月和10月收治的30例癫痫患者进行回顾性病历审查,以确定6个来源中的无意用药差异:记录的用药史、电子病历中的住院医嘱、门诊病历、住院病史和入院文件、电话留言记录以及外部保险理赔。

结果

共有63%的患者至少存在1处无意用药差异。大多数差异发生在每日维持性抗惊厥药物方面(63%)。最常见的类型是用药史遗漏(31%)和住院医嘱遗漏(27%)。不同药剂师、护士和医生完成的存在至少1处差异的用药史数量有所不同,但差异无统计学意义。

结论

我们的研究发现,与之前的研究相比,抗惊厥药物差异的发生率更高。这项质量改进举措确定缺乏标准化流程是癫痫患儿入院时抗惊厥药物差异发生率高的根本原因。