Omololu Ayanfe, Ojelade Barakah, Ajayi Oluwatomiwa, Adesomi Tolu, Alade Oreoluwa, Adebisi Segun, Nwadike Victor
Department of Internal Medicine, Federal Medical Center, Abeokuta, Nigeria.
Department of Clinical Microbiology, Federal Medical Center, Abeokuta, Nigeria.
SAGE Open Med Case Rep. 2021 May 16;9:2050313X211015494. doi: 10.1177/2050313X211015494. eCollection 2021.
Coronavirus disease 2019 is a novel disease currently ravaging the world as a pandemic. More emphasis has been focused on the acute disease, with less attention on the detection and management of long-term sequelae which develop in some patients, variously termed "Long COVID," Post-coronavirus disease 2019 syndrome, or ongoing coronavirus disease. There are also various reports in the literature on the duration of viral shedding, with the longest known recorded being about 70 days, and whether this duration has an effect on prognosis or patients remaining infectious is still unknown. We report the case of a 22-year-old health care worker with prolonged multi-systemic features of coronavirus disease 2019 including cardiovascular, respiratory, central nervous system, and musculoskeletal symptoms lasting about 18 weeks from symptom onset, though never hospitalized, and persistent detection of severe acute respiratory syndrome coronavirus 2 attributed to viral shedding for over 110 days, which is the longest duration recorded to our knowledge.
2019冠状病毒病是一种目前作为大流行病肆虐全球的新型疾病。更多的重点一直放在急性疾病上，而对一些患者出现的长期后遗症的检测和管理关注较少，这些后遗症有各种不同的称谓，如“长新冠”、2019冠状病毒病后综合征或持续性冠状病毒病。文献中也有关于病毒脱落持续时间的各种报道，已知最长记录约为70天，而这个持续时间是否对预后有影响或患者是否仍具传染性仍不清楚。我们报告了一例22岁医护人员的病例，该患者具有2019冠状病毒病的长期多系统特征，包括心血管、呼吸、中枢神经系统和肌肉骨骼症状，从症状出现起持续约18周，虽未住院，但严重急性呼吸综合征冠状病毒2因病毒脱落持续检测超过110天，据我们所知这是记录到的最长持续时间。
