Department of Immunology, Landspitali-The National University Hospital of Iceland, Reykjavik, Iceland.
Department of Medicine, Faculty of Medicine, University of Iceland, Reykjavik, Iceland.
Front Public Health. 2022 Aug 12;10:934242. doi: 10.3389/fpubh.2022.934242. eCollection 2022.
From the beginning of the COVID-19 pandemic, it has claimed over 6 million lives, and globally the pandemic rages with detrimental consequences, with the emergence of new more infectious and possibly virulent variants. A clinical obstacle in this battle has been to determine when an infected individual has reached a non-infectious state. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) can be transmitted under diverse circumstances, and various rules and regulations, along with different testing methods, have been applied in an attempt to confine the transmission. However, that has proven to be a difficult task. In this review, we take together recently published data on infectivity and transmission of SARS-CoV-2 and have combined it with the clinical experience that physicians in Iceland have accumulated from the pandemic. In addition, we suggest guidelines for determining when patients with COVID-19 reach a non-infectious state based on a combination of clinical experience, scientific data, and proficient use of available tests. This review has addressed some of the questions regarding contagiousness and immunity against SARS-CoV-2.
自 COVID-19 大流行开始以来，它已导致超过 600 万人死亡，并且在全球范围内，大流行仍在肆虐，造成了新的更具传染性和可能更具毒性的变异。这场战斗中的一个临床障碍是确定感染个体何时达到非传染性状态。严重急性呼吸系统综合症冠状病毒 2（SARS-CoV-2）可以在不同情况下传播，并且已经应用了各种规则和法规以及不同的测试方法来试图限制传播。然而，事实证明这是一项艰巨的任务。在这篇综述中，我们综合了最近发表的关于 SARS-CoV-2 传染性和传播性的数据，并结合了冰岛医生从大流行中积累的临床经验。此外，我们根据临床经验、科学数据和熟练使用现有测试的方法，提出了确定 COVID-19 患者何时达到非传染性状态的指南。这篇综述解决了一些关于 SARS-CoV-2 传染性和免疫力的问题。
