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芦丁和维生素C治疗色素性紫癜性苔藓样皮炎

Rutoside and Ascorbic Acid in the Treatment of Schamberg Pigmented Purpuric Dermatosis.

作者信息

Morquette Alexandra J, Lee Jason B, Grossman Shoshana K, Hsu Sylvia

机构信息

Dermatology, Temple University Lewis Katz School of Medicine, Philadelphia, USA.

Dermatology and Cutaneous Biology, Thomas Jefferson University, Philadelphia, USA.

出版信息

Cureus. 2021 Apr 20;13(4):e14592. doi: 10.7759/cureus.14592.

Abstract

Schamberg disease is a type of pigmented purpuric dermatosis (PPD), which is a benign cutaneous capillaritis characterized by macules and patches most commonly found on the lower extremities. Rutoside and ascorbic acid have been shown in previous cases to be efficacious in the treatment of PPD lesions due to their free radical scavenging effect on capillaries. We present the case of a 19-year-old woman with Schamberg disease who achieved complete clearance of lesions within four months of daily rutoside and ascorbic acid treatment. The goal of this case report is to further demonstrate the effectiveness of this treatment and to call for investigation of its use as a standard of care in PPD.

摘要

色素性紫癜性皮病(PPD)是一种良性皮肤毛细血管炎,最常见于下肢,表现为斑点和斑片。舍恩伯格病是色素性紫癜性皮病的一种类型。在之前的病例中,芦丁和抗坏血酸因其对毛细血管的自由基清除作用,已被证明对治疗PPD病变有效。我们报告了一名19岁舍恩伯格病女性患者,在每日服用芦丁和抗坏血酸治疗四个月内病变完全消退。本病例报告的目的是进一步证明这种治疗方法的有效性,并呼吁对其作为PPD标准治疗方法的应用进行研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab78/8136452/9d8ddeb9ec69/cureus-0013-00000014592-i01.jpg

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