Cannon S R, Dyson P H, Sanderson P J
Royal National Orthopaedic Hospital, Stanmore, Middlesex, England.
J Bone Joint Surg Br. 1988 Aug;70(4):600-2. doi: 10.1302/0301-620X.70B4.3403605.
We report 16 orthopaedic patients who had antibiotic-associated diarrhoea (pseudomembranous colitis) after operation. There was an association with the use of cephradine and with the prolongation of prophylaxis for more than three peri-operative doses. Five cases occurred as a cluster, suggesting that the causative agent, Clostridium difficile, may be infectious in some situations.
我们报告了16例骨科患者，他们术后发生了抗生素相关性腹泻（伪膜性结肠炎）。这与头孢拉定的使用以及预防性用药超过三个围手术期剂量的延长有关。有5例为聚集性发生，提示病原体艰难梭菌在某些情况下可能具有传染性。
