Roberts A P, Hughes A W
Int Orthop. 1985;8(4):299-302. doi: 10.1007/BF00266876.
A woman underwent joint replacement surgery with prophylactic antibiotic cover, and subsequently died as a result of pseudomembranous colitis. We have noted a high incidence of antibiotic diarrhoea with cephradine, and suggest that if administration of prophylactic antibiotics is restricted to 3 days or less, the incidence of diarrhoea would diminish, and the therapeutic value of the antibiotics would be maintained.
一名女性在接受关节置换手术并使用预防性抗生素后，随后因伪膜性结肠炎死亡。我们注意到头孢拉定导致抗生素相关性腹泻的发生率很高，并建议如果将预防性抗生素的使用时间限制在3天或更短时间内，腹泻的发生率将会降低，同时抗生素的治疗价值将得以维持。
