European Society for Environmental and Occupational Medicine, University of Hamburg, Berlin, Germany.
Drexel University School of Public Health, Philadelphia, Pennsylvania, USA.
Am J Ind Med. 2021 Jul;64(7):543-550. doi: 10.1002/ajim.23257. Epub 2021 May 25.
Malignant mesothelioma (MM) is one of the most aggressive cancers with the poorest of outcomes. There is no doubt that mesothelioma in males is related to asbestos exposure, but some authors suggest that most of the cases diagnosed in females are "idiopathic." In our assessment of the science, the "low risk" of mesothelioma in females is because of the nonsystematic recording of exposure histories among females. Indeed, asbestos exposure is mentioned in only some of the studies that include females. We estimate the risk of MM among females to be close to that in males. The absence of detailed exposure histories should be rectified in future studies involving women. As a matter of social justice, the ongoing failure to recognize asbestos as the cause of a majority of cases of MM in females does them, and their kin, a profound disservice.
恶性间皮瘤（MM）是最具侵袭性的癌症之一，预后最差。毫无疑问，男性间皮瘤与石棉暴露有关，但一些作者认为，大多数女性诊断出的病例是“特发性的”。在我们对科学的评估中，女性间皮瘤的“低风险”是由于女性接触史的非系统性记录。事实上，只有部分包含女性的研究提到了石棉暴露。我们估计女性间皮瘤的风险接近男性。在未来涉及女性的研究中，应该纠正缺乏详细接触史的问题。作为社会公正的问题，目前未能认识到石棉是女性大多数间皮瘤病例的原因，这对她们及其亲属造成了极大的伤害。
