Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi 110 029, India.
Institute of Gastroenterology, Pushpawati Singhania Hospital and Research Institute, Sheikh Sarai Phase 2, New Delhi, 110 017, India.
Indian J Gastroenterol. 2021 Jun;40(3):253-264. doi: 10.1007/s12664-021-01163-x. Epub 2021 May 26.
The role of diet and its manipulation in the management of inflammatory bowel disease (IBD) is gradually acquiring central stage. Certain dietary factors have been identified as putative triggers in IBD as some other factors are found to be protective. The dietary manipulation as part of comprehensive IBD care should be done by the clinician in conjunction with a skilled dietitian. Nutritional deficiencies are common in patients with IBD and can have long-term effects on disease course and quality of life in these patients. So, early identification and correction of these deficiencies along with proper nutritional supplementation should be addressed routinely as a part of IBD management. Oral nutritional supplementation is sufficient for most patients, but in some sick patients, tube feeding may be necessary. Diet needs to be individualized based on the nutritional deficiencies and dietary triggers in a specific patient. Multiple specific diets, with elimination of components that trigger inflammation or addition of components that alter gut microbes in a favorable way, are now appearing as a treatment option in IBD, but more evidence is required before their universal recommendation. Though enteral nutrition (EN) (both exclusive enteral nutrition [EEN] and partial enteral nutrition [PEN]) have proven therapeutic role in pediatric IBD, their uses and role are now expanding in adult IBD patients as well.
饮食及其干预在炎症性肠病(IBD)管理中的作用逐渐占据核心地位。某些饮食因素已被确定为 IBD 的潜在诱因,而其他一些因素则被认为具有保护作用。饮食干预作为综合 IBD 护理的一部分,应由临床医生与熟练的营养师共同进行。IBD 患者中常见营养缺乏,并可能对这些患者的疾病进程和生活质量产生长期影响。因此,应常规早期识别和纠正这些缺乏,并进行适当的营养补充,作为 IBD 管理的一部分。口服营养补充对于大多数患者足够,但在一些病情严重的患者中,可能需要管饲。饮食需要根据特定患者的营养缺乏和饮食诱因进行个体化。多种特定饮食,消除引发炎症的成分或添加以有利方式改变肠道微生物的成分,现已成为 IBD 的一种治疗选择,但在广泛推荐之前,还需要更多的证据。尽管肠内营养(EN)(包括完全肠内营养[EEN]和部分肠内营养[PEN])已被证明在儿科 IBD 中有治疗作用,但现在在成人 IBD 患者中也在扩大其用途和作用。