Saleem Zikria, Godman Brian, Azhar Faiza, Kalungia Aubrey C, Fadare Joseph, Opanga Sylvia, Markovic-Pekovic Vanda, Hoxha Iris, Saeed Amna, Al-Gethamy Manal, Haseeb Abdul, Salman Muhammad, Khan Ayaz Ali, Nadeem Muhammad Umer, Rehman Inaam Ur, Qamar Muhammad Usman, Amir Afreenish, Ikram Aamer, Hassali Muhammad Azmi
Department of Pharmacy Practice, Faculty of Pharmacy, The University of Lahore, Lahore, Pakistan.
Strathclyde Institute of Pharmacy and Biomedical Sciences, Strathclyde University, Glasgow, UK.
Expert Rev Anti Infect Ther. 2022 Jan;20(1):71-93. doi: 10.1080/14787210.2021.1935238. Epub 2021 Jul 26.
The emergence of antimicrobial resistance (AMR) is a threat to public health. In 2015, the World Health Organization (WHO) introduced a global action plan to tackle AMR in the World Health Assembly. Pakistan's national action plan (NAP) for AMR was released in May 2017 by the Ministry of National Health Services. Based on the NAP, strategies have been initiated on a national and provincial scale in Pakistan.
This narrative review of the five components of the Pakistan NAP has been undertaken to discuss some of the challenges in implementation of the NAP for AMR in Pakistan including different opinions and views of key stakeholders, combined with suggestions on potential ways to reduce the burden of the AMR.
Going forward, healthcare authorities should focus on screening and monitoring of all the objectives of the NAP by establishing proper policies as well as promoting antimicrobial stewardship interventions and Infection prevention and control (IPC) practices. Overall, the comprehensive strengthening of the healthcare system is required to adequately implement the NAP, tackle continued inappropriate antimicrobial use and high AMR rates in Pakistan.
抗菌药物耐药性(AMR)的出现对公共卫生构成威胁。2015年,世界卫生组织(WHO)在世界卫生大会上推出了一项应对AMR的全球行动计划。巴基斯坦国家卫生服务部于2017年5月发布了巴基斯坦AMR国家行动计划(NAP)。基于该NAP,巴基斯坦已在国家和省级层面启动了相关战略。
本文对巴基斯坦NAP的五个组成部分进行了叙述性综述,旨在讨论巴基斯坦实施AMR NAP过程中面临的一些挑战,包括关键利益相关者的不同意见和观点,并结合关于减轻AMR负担的潜在方法的建议。
展望未来,卫生保健当局应通过制定适当政策以及促进抗菌药物管理干预措施和感染预防与控制(IPC)实践,专注于对NAP的所有目标进行筛查和监测。总体而言,需要全面加强卫生保健系统,以充分实施NAP,应对巴基斯坦持续存在的抗菌药物使用不当和高AMR率问题。