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埃塞俄比亚南贡德尔地区医院接受脊髓麻醉下剖宫产分娩的产妇术中恶心呕吐的发生率及相关因素

Magnitude and associated factors of intraoperative nausea and vomiting among parturients who gave birth with cesarean section under spinal anesthesia at South Gondar zone Hospitals, Ethiopia.

作者信息

Chekol Basazinew, Zewudu Fentaye, Eshetie Denberu, Temesgen Netsanet, Molla Eshetie

机构信息

Department of Anesthesia, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.

Department of Social Public Health, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia.

出版信息

Ann Med Surg (Lond). 2021 May 16;66:102383. doi: 10.1016/j.amsu.2021.102383. eCollection 2021 Jun.

DOI:10.1016/j.amsu.2021.102383
PMID:34040769
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8143994/
Abstract

BACKGROUND

Intraoperative nausea and vomiting are common intraoperative events by which parturient feel discomfort and disturbed after spinal anesthesia.

METHODS

Hospital-based cross-sectional study was conducted on mothers who underwent cesarean section with spinal anesthesia. Descriptive analysis and chi-square test were employed. Bivariable and multivariable logistic regressions were used to measure the association of factors with the outcome variable intraoperative nausea and vomiting. A p-value of ≤0.05 was used to decide statistical significance for multivariable logistic regression.

RESULT

A total of 246 parturients were participated in this study. The incidence of intraoperative nausea and vomiting was 40.2%. According to multivariable logistic regression, age greater than 30 years (AOR, 6.26; 95%CI, 2.2-17.78; p-value 0.001), primiparous (AOR, 3.72; 95%CI, 1.35-10.24; p-value, 0.011), having motion sickness (AOR, 7.1; 95%CI, 2.75-18.33; p-value 0.001), emergency cesarean sectin (AOR, 9.85; 95%CI, 3.19-30.38; p-value 0.001), oxygen suplimentation (AOR, 0.021; 95%CI, 0.005-0.08; p-value 0.0001) and uterotonic agent (AOR, 2.99; 95%CI 1.24-7.22; p-value 0.015) had statistically significant association with intraoperative nausea and vomiting.

CONCLUSION

In our study, the overall incidence of intraoperative nausea and vomiting after spinal anesthesia was 40.2%. Parturients with age greater than 30 years, having motion sickness, didn't get intraoperative supplemental oxygen, oxytocin used for the uterotonic purpose, emergency surgery, and primiparous were at increased risk of intraoperative nausea and vomiting.

摘要

背景

术中恶心呕吐是常见的术中事件,产妇在脊髓麻醉后会感到不适和困扰。

方法

对接受脊髓麻醉剖宫产的母亲进行基于医院的横断面研究。采用描述性分析和卡方检验。双变量和多变量逻辑回归用于衡量因素与结果变量术中恶心呕吐之间的关联。多变量逻辑回归的p值≤0.05用于确定统计学意义。

结果

共有246名产妇参与本研究。术中恶心呕吐的发生率为40.2%。根据多变量逻辑回归,年龄大于30岁(比值比[AOR],6.26;95%置信区间[CI],2.2 - 17.78;p值0.001)、初产妇(AOR,3.72;95%CI,1.35 - 10.24;p值,0.011)、有晕动病(AOR,7.1;95%CI,2.75 - 18.33;p值0.001)、急诊剖宫产(AOR,9.85;95%CI,3.19 - 30.38;p值0.001)、吸氧(AOR,0.021;95%CI,0.005 - 0.08;p值0.0001)和宫缩剂(AOR,2.99;95%CI 1.24 - 7.22;p值0.015)与术中恶心呕吐有统计学显著关联。

结论

在我们的研究中,脊髓麻醉后术中恶心呕吐的总体发生率为40.2%。年龄大于30岁、有晕动病、未术中吸氧、使用缩宫素进行宫缩、急诊手术以及初产妇的产妇术中恶心呕吐风险增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e263/8143994/2ead05397ad9/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e263/8143994/2ead05397ad9/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e263/8143994/2ead05397ad9/gr1.jpg

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