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Heyneanine hydroxyindolenine, a new indole alkaloid from Ervatamia coronaria var. plena.

作者信息

Sharma P, Cordell G A

机构信息

Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 60612.

出版信息

J Nat Prod. 1988 May-Jun;51(3):528-31. doi: 10.1021/np50057a012.

DOI:10.1021/np50057a012
PMID:3404150
Abstract

The whole plant of Ervatamia coronaria var. plena obtained from Thailand has afforded a new indole alkaloid 19S-heyneanine hydroxyindolenine whose structure was deduced through interpretation of spectral data. Nine known alkaloids, coronaridine, coronaridine hydroxyindolenine, voacangine, voacangine hydroxyindolenine, heyneanine, voacristine, 3-oxo-coronaridine, 3-oxo-voacangine,and voacristine hydroxyindolenine, and six common triterpenoids were also isolated. Coronaridine was the principal cytotoxic alkaloid obtained.

摘要

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