is an assistant clinical professor at Northeastern University in Boston, Massachusetts, and a staff nurse anesthetist at Good Samaritan Medical Center in Brockton, Massachusetts. Email:
is the chair of the Department of Anesthesiology at Good Samaritan Medical Center in Brockton, Massachusetts.
AANA J. 2021 Jun;89(3):205-212.
Increasing numbers of patients are using cannabis before procedures that require anesthesia. This study set out to examine the impact of cannabis use on anesthetic agent requirements, associated cardiac and respiratory morbidity, and overall satisfaction levels in patients undergoing esophagogastroduodenoscopy (EGD). This involved a retrospective review of patients undergoing EGD at a single center. Fortyseven, self-reported cannabis users were identified and 23 were successfully cross-matched with control participants for comparison purposes. The Wilcoxon signed rank test was used to evaluate differences in propofol administration between the 2 groups, and the McNemar test was used to test for differences in fentanyl and ketamine administration. No statistically significant differences were observed in propofol, fentanyl, or ketamine administration in the cannabis group compared with the control group. No adverse cardiac or respiratory events were reported within 30 days for either group. This study was specific to EGD procedures of short duration, and larger studies are needed to confirm results of no consequence in cannabis users undergoing anesthesia. Future studies should consider cannabis users who undergo anesthesia for diverse procedure types of various durations.
越来越多的患者在需要麻醉的手术前使用大麻。本研究旨在检查大麻使用对接受食管胃十二指肠镜检查（EGD）的患者的麻醉剂需求、相关心脏和呼吸发病率以及总体满意度的影响。这涉及对单个中心接受 EGD 的患者进行的回顾性研究。确定了 47 名自我报告的大麻使用者，并成功地将 23 名与对照组患者进行了交叉匹配以进行比较。Wilcoxon 符号秩检验用于评估两组之间异丙酚给药的差异，McNemar 检验用于检验芬太尼和氯胺酮给药的差异。与对照组相比，大麻组在异丙酚、芬太尼或氯胺酮给药方面没有观察到统计学上的显著差异。两组均未报告 30 天内出现心脏或呼吸不良事件。本研究针对持续时间较短的 EGD 手术，需要更大的研究来证实接受麻醉的大麻使用者没有后果的结果。未来的研究应考虑接受不同持续时间和不同类型手术的麻醉的大麻使用者。
