Arendt J, Ravault J P
Department of Biochemistry, University of Surrey, Guildford, England.
J Pineal Res. 1988;5(3):245-50. doi: 10.1111/j.1600-079x.1988.tb00650.x.
The intensity of cool, white, fluorescent light required to suppress melatonin secretion in Ile-de-France rams was investigated. Animals were conditioned to 12L:12D, lights on 0600 hours, 104 microW/cm2 (350 lux) at eye level and subjected to a 1-hour light pulse beginning 3 hours after lights off. Plasma melatonin measurements indicated that secretion was significantly suppressed by 0.30, 7.46, and 26.32 microW/cm2 (1.02, 25.10, and 88.60 lux, respectively) but not by 0.043 microW/cm2 (0.15 lux). A clear dose-response relationship was apparent between light intensity and degree of melatonin suppression.
研究了抑制法兰西岛公羊褪黑素分泌所需的冷白色荧光灯强度。动物适应了12小时光照：12小时黑暗的周期，早上6点开灯，眼睛水平处光照强度为104微瓦/平方厘米（350勒克斯），并在熄灯3小时后开始进行1小时的光脉冲照射。血浆褪黑素测量结果表明，分泌受到显著抑制的光照强度分别为0.30、7.46和26.32微瓦/平方厘米（分别为1.02、25.10和88.60勒克斯），但0.043微瓦/平方厘米（0.15勒克斯）的光照强度未产生抑制作用。光照强度与褪黑素抑制程度之间存在明显的剂量反应关系。
