某大型医学住院医师培训计划内科学住院医师中 SARS-CoV-2 的血清流行率。
Seroprevalence of SARS-CoV-2 among Internal Medicine Residents at a Major Academic Medicine Residency Program.
机构信息
Department of Medicine, Brown University, Providence, RI.
Department of Medicine, Brown University, Providence, RI; Rhode Island Department of Health.
出版信息
R I Med J (2013). 2021 Jun 1;104(5):20-23.
BACKGROUND
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and its associated disease (COVID-19) are a significant cause of morbidity and mortality across the United States. Internal medicine (IM) residents are a critical component of the healthcare workforce yet their seroprevalence of SARS-CoV-2 antibodies is largely unknown. The aim of this research was to ascertain the seroprevalences of SARS-CoV-2 among internal medicine residents during the first peak of COVID-19.
METHODS
IM residents were enrolled in a surveillance program that included PCR and antibody testing for SARS-CoV-2 in June 2020. Residents also completed a short questionnaire to obtain sociodemographic information and characterize potential workplace exposure to COVID-19.
RESULTS
A total of 101 IM residents participated in the study (out of N=162). Of the 101 samples, three (2.9%) tested positive for SARS-CoV-2 antibodies. No residents tested PCR positive for SARS-CoV-2.
DISCUSSION
The implementation of COVID-19 patient cohorting and the incorporation of telemedicine to communicate with hospitalized patients into clinical practice early in the pandemic may have prevented the spread of the virus among the surveyed clinical trainees.
CONCLUSION
Despite significant engagement with COVID-19 patients, IM residents demonstrated a low rate of SARS-CoV-2 seroprevalence.
背景
严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）及其相关疾病（COVID-19）是美国发病率和死亡率的重要原因。内科（IM）住院医师是医疗保健工作者的重要组成部分，但他们对 SARS-CoV-2 抗体的血清阳性率在很大程度上是未知的。本研究的目的是确定 COVID-19 第一波期间内科住院医师中 SARS-CoV-2 的血清阳性率。
方法
2020 年 6 月，内科住院医师参加了一项监测计划，该计划包括对 SARS-CoV-2 的 PCR 和抗体检测。住院医师还完成了一份简短的问卷，以获取社会人口统计学信息并描述潜在的 COVID-19 工作场所暴露情况。
结果
共有 101 名内科住院医师参加了这项研究（共 162 名）。在 101 个样本中，有 3 个（2.9%）检测出 SARS-CoV-2 抗体呈阳性。没有居民的 SARS-CoV-2 PCR 检测呈阳性。
讨论
在大流行早期，将 COVID-19 患者分组和将远程医疗纳入与住院患者的沟通纳入临床实践，可能阻止了调查中的临床受训者中病毒的传播。
结论
尽管与 COVID-19 患者密切接触，但 IM 住院医师的 SARS-CoV-2 血清阳性率仍然较低。
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