Samia Arthur M, Donthi Deepak, Nenow Joseph, Malik Preeti, Prenshaw Karyn
Department of Pathology and Laboratory Medicine, Brody School of Medicine/East Carolina University, Greenville, USA.
Department of Pathology and Laboratory Medicine, Vidant Medical Center/East Carolina University, Greenville, USA.
Cureus. 2021 Apr 22;13(4):e14634. doi: 10.7759/cureus.14634.
Syringomas are benign tumors originating from the intraepidermal portion of eccrine sweat ducts. A six-year-old African American female presented with multiple 2-3 mm hyperpigmented papules over the neck, upper chest, and axillae bilaterally. The lesions were non-tender, non-pruritic, and did not bleed when lightly scraped. A café-au-lait macule was incidentally found in the mid-back of the patient. Histopathologically, multiple small ducts displaying a tadpole-shaped/paisley-tie pattern with fibrotic stroma were identified on hematoxylin and eosin staining. Epithelium showing nests of cells with basaloid appearance and dilated glands filled with eosinophilic material were also identified. These histopathologic findings were consistent with a diagnosis of eruptive syringoma. The patient was treated conservatively, and the lesions subsided without intervention. In most patients requesting treatment, isotretinoin is used; however, this may be an unnecessary measure in many patients. Overall, this case was significant due to the patient's young age, ethnicity, and clinical improvement in the absence of treatment.
汗管瘤是起源于小汗腺导管表皮内部分的良性肿瘤。一名6岁非裔美国女性双侧颈部、上胸部及腋窝出现多个2 - 3毫米的色素沉着丘疹。这些损害无压痛、无瘙痒,轻刮时不出血。患者背部中部偶然发现一个咖啡斑。组织病理学上,苏木精-伊红染色显示多个小导管呈蝌蚪形/佩斯利领带样图案并伴有纤维化间质。还发现上皮细胞呈基底样外观巢状排列以及充满嗜酸性物质的扩张腺体。这些组织病理学表现符合爆发性汗管瘤的诊断。患者接受了保守治疗,损害未经干预自行消退。在大多数要求治疗的患者中,使用异维甲酸;然而,这对许多患者可能是不必要的措施。总体而言,该病例因患者年龄小、种族以及未经治疗临床症状改善而具有重要意义。