Li Zi-Wei, Sang Chen-Chen, Sun Biao, Tian Hai-Yan, Zhang Xiao-Qi, Ye Wen-Cai
Institute of Traditional Chinese Medicine & Natural Products, and Guangdong Engineering Research Center for Modernization of Traditional Chinese Medicine(TCM), College of Pharmacy, Jinan University Guangzhou 510632, China.
Institute of Traditional Chinese Medicine & Natural Products, and Guangdong Engineering Research Center for Modernization of Traditional Chinese Medicine(TCM), College of Pharmacy, Jinan University Guangzhou 510632, China NMPA Key Laboratory for Quality Evaluation of TCM (Traditional Chinese Patent Medicine) Guangzhou 510632, China.
Zhongguo Zhong Yao Za Zhi. 2021 May;46(10):2509-2513. doi: 10.19540/j.cnki.cjcmm.20210125.602.
In order to study the alkaloids from branches and leaves of Ervatamia hainanensis, silica gel, ODS, Sephadex LH-20 and HPLC chromatography were used to obtain six alkaloids from the branches and leaves of E. hainanensis with use of. Based on the physicochemical properties and spectral data, their structures were identified as 10-hydroxydemethylhirsuteine(1), 3R-hydroxycoronaridine(2), 3-(2-oxopropyl)coronaridine(3), pandine(4), 16-epi-vobasine(5), and 16-epi-vobasinic acid(6). Among them, compound 1 was a new monoterpenoid indole alkaloid, and compounds 5 and 6 were obtained from this plant for the first time.
为研究海南狗牙花枝叶中的生物碱，采用硅胶柱色谱、ODS柱色谱、葡聚糖凝胶LH - 20柱色谱和高效液相色谱法，从海南狗牙花枝叶中分离得到6种生物碱。根据其理化性质和光谱数据，鉴定它们的结构分别为10 - 羟基去甲基毛果芸香碱(1)、3R - 羟基冠狗牙花定(2)、3 - (2 - 氧代丙基)冠狗牙花定(3)、潘定(4)、16 - 表沃巴碱(5)和16 - 表沃巴酸(6)。其中，化合物1是一种新的单萜吲哚生物碱，化合物5和6首次从该植物中获得。
