Chang Li-Kun, Zhang Wen-Jin, Cao Ye, Wang Sheng, Kang Chuan-Zhi, Zhou Li, Yang Quan, Zhou Liang-Yun, Guo Lan-Ping
School of Traditional Chinese Medicine, Guang Dong Pharmaceutical University Guangzhou 510006, China National Resource Center for Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
National Resource Center for Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
Zhongguo Zhong Yao Za Zhi. 2021 May;46(9):2133-2141. doi: 10.19540/j.cnki.cjcmm.20210108.603.
Atractylodis Rhizoma(AR) is a traditional Chinese medicinal material for food and medicine, with the functions of eli-minating dampness, strengthening the spleen, expelling wind evil and dispersing cold. AR contains a variety of compounds, including sesquiterpenoids, alkynes, triterpenoids, aromatic glycosides, polysaccharides and so on. At present, the researches on AR mainly focus on volatile components, with relatively fewer researches on non-volatile components. Polysaccharide from Atractylodis Rhizoma(ARP) is an important material basis among non-volatile components for the efficacy. Due to its many biological activities such as immunomodulatory activity, anti-tumors, anti-virus and anti-oxidation, ARP has certain research value and potential. The diversity of the polysaccharide structure is the basis for biological functions, but it also increases the difficulty of carbohydrate research. The research on the extraction, separation, purification, structure and activity of ARP is in the preliminary exploration stage, still with many shortcomings. Herein, recent advancements in the extraction, purification, structural characteristics and biological activities of ARP were summarized in this article to provide scientific reference for the in-depth systematic research of ARP and the development of AR resources.
白术是一种药食两用的传统中药材，具有祛湿、健脾、祛风散寒的功效。白术含有多种化合物，包括倍半萜类、炔类、三萜类、芳香糖苷、多糖等。目前，对白术的研究主要集中在挥发性成分上，对非挥发性成分的研究相对较少。白术多糖是白术非挥发性成分中发挥药效的重要物质基础。由于白术多糖具有免疫调节、抗肿瘤、抗病毒、抗氧化等多种生物学活性，具有一定的研究价值和潜力。多糖结构的多样性是其生物学功能的基础，但也增加了糖类研究的难度。白术多糖的提取、分离、纯化、结构及活性研究尚处于初步探索阶段，仍存在诸多不足。本文综述了白术多糖在提取、纯化、结构特征及生物学活性方面的研究进展，为白术多糖的深入系统研究及白术资源开发提供科学参考。
