Liu Shan-Shan, Guo Jie, Li Zong-Ai, Tian Shuang-Shuang, Zhu Jing-Jing, Yan Li-Hua, Wang Zhi-Min, Gao Lu
National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicines, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China.
National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicines, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences Beijing 100700, China Tianjin University of Traditional Chinese Medicine Tianjin 300193, China.
Zhongguo Zhong Yao Za Zhi. 2020 Apr;45(7):1578-1595. doi: 10.19540/j.cnki.cjcmm.20190616.201.
Alismatis Rhizoma is a traditional Chinese medicine, which was widely used in clinical prescriptions and proprietary Chinese medicine. Over 220 compounds have been isolated from it, including triterpenoids, sesquiterpenoids, diterpenoids, polysaccharides, nitrogen compounds, phenylpropanoids, flavones and sterides. The pharmacological studies show that Alismatis Rhizoma exhibits diuretic, anti-urolithiatic, anti-hyperlipidemia, antidiabetics, antitumor, antioxidative, anti-inflammatory, anti-complementary activities, etc. In this review, the chemical compositions and its pharmacological activities of Alismatis Rhizoma in recent 50 years were summarized. The authors hope to provide references for further study, development and utilization of Alismatis Rhizoma.
泽泻是一种传统中药，广泛应用于临床方剂和中成药中。已从其中分离出220多种化合物，包括三萜类、倍半萜类、二萜类、多糖、含氮化合物、苯丙素类、黄酮类和甾体类。药理研究表明，泽泻具有利尿、抗尿路结石、抗高脂血症、抗糖尿病、抗肿瘤、抗氧化、抗炎、抗补体活性等作用。本文综述了近50年来泽泻的化学成分及其药理活性。作者希望为泽泻的进一步研究、开发和利用提供参考。
