抗反流和内镜治疗 Barrett 食管和表浅性食管肿瘤。

Antireflux and Endoscopic Therapies for Barrett Esophagus and Superficial Esophageal Neoplasia.

机构信息

MedStar Franklin Square Medical Center, 9000 Franklin Square Drive, Department of Surgery, Baltimore, MD 21237, USA.

MedStar Georgetown University Hospital, 3800 Reservoir Rd, NW, 4PHC Department of Surgery, Washington, DC 20007, USA.

出版信息

Surg Clin North Am. 2021 Jun;101(3):391-403. doi: 10.1016/j.suc.2021.03.002.

DOI:10.1016/j.suc.2021.03.002

PMID:34048760

Abstract

Barrett esophagus (BE), defined as intestinal metaplasia of the distal esophageal mucosa, typically results from chronic gastroesophageal reflux disease and is the only known precursor of esophageal adenocarcinoma. The standard of care for the management of early esophageal neoplasia in the setting of BE has changed drastically over the past 15 years. Further investigation into diagnostic and therapeutic adjuncts will continue to improve our ability to control or cure BE before its advancement to a life-threatening malignancy.

摘要

巴雷特食管（BE）是指远端食管黏膜的肠化生，通常由慢性胃食管反流病引起，是食管腺癌唯一已知的前体。在 BE 背景下，早期食管肿瘤的管理标准在过去 15 年中发生了巨大变化。进一步研究诊断和治疗辅助手段将继续提高我们在 BE 进展为危及生命的恶性肿瘤之前控制或治愈它的能力。