Afternoon aerobic and resistance exercise have limited impact on 24-h CGM outcomes in adults with type 1 diabetes: A secondary analysis.

AIMS

This study examined post-exercise glycemic variability in individuals with type 1 diabetes after acute bouts of resistance (RE) and aerobic exercise (AE) compared to a no-exercise day (CON). We hypothesized that exercise days would have greater glucose variability (standard deviation - SD, coefficient of variation - CV), and less time in range (TIR), compared to CON.

METHODS

A secondary analysis was conducted on previously collected data. Twelve active participants with type 1 diabetes performed three testing sessions in random order with at least 48 h in between: AE (45-min treadmill run at 60%VO), RE (three sets of eight repetitions, seven weight-lifting exercises), and CON (45-min no-exercise control). Interstitial glucose levels were monitored by blinded continuous glucose monitoring (CGM). Glycemic variability was evaluated for 0-6 h, overnight (00:00-06:00) and 24 h after exercise.

RESULTS

Mean CGM glucose, TIR, and time above/below range were similar among conditions (P > 0.05). Lower SD (0.8 [0.5-1.1], 1.4 [0.9-2.4]mmol/L, p = 0.009) and CV (11.4 [8.6-15.3], 23.4 [13.7-31.6]%, p = 0.007) were found overnight after AE versus CON. Otherwise, AE and RE had limited impact on post-exercise glycemia.

CONCLUSIONS

Acute RE and AE bouts may have limited impact on post-exercise glycemic variability compared to rest in habitually active individuals with type 1 diabetes.