Department of Nephrology, Dezhou People's Hospital, Dezhou, China.
Department of Blood Transfusion, Dezhou People's Hospital, Dezhou, China.
J Int Med Res. 2021 May;49(5):3000605211016627. doi: 10.1177/03000605211016627.
The present meta-analysis aimed to determine the relationship between intra-abdominal hypertension (IAH) and an increased prevalence of acute kidney injury (AKI) and identify the associated risk factors in various patient populations, regardless of whether they were admitted to an intensive care unit.
We used three databases for the following search terms: "IAH," "abdominal compartment syndrome," "AKI," "acute kidney failure," and others. The articles retrieved were compared to identify appropriate studies published until 7 May 2020. The main outcome was AKI.
Six studies with 344 individuals were included. The patients were divided into two main groups: the IAH and non-IAH groups. Compared with patients without IAH, patients with IAH had a higher risk of AKI (odds ratio = 2.57, 95% confidence interval: 1.55-4.26). In the subgroup and meta-regression analyses, body mass index, age, the presence or absence of burns, and cardiac surgery did not affect the risk of AKI.
IAH was associated with AKI risk, and this association was not influenced by age, body mass index, the presence or absence of burns, or cardiac surgery.
本荟萃分析旨在确定腹腔内高压（IAH）与急性肾损伤（AKI）患病率增加之间的关系，并确定各种患者人群（无论是否入住重症监护病房）的相关危险因素。
我们使用三个数据库，检索了以下搜索词：“IAH”、“腹腔间隔室综合征”、“AKI”、“急性肾衰竭”等。比较检索到的文章，以确定截至 2020 年 5 月 7 日发表的合适研究。主要结局为 AKI。
纳入了 6 项共 344 人的研究。患者分为 IAH 和非 IAH 两组。与无 IAH 的患者相比，IAH 患者发生 AKI 的风险更高（比值比=2.57，95%置信区间：1.55-4.26）。在亚组和荟萃回归分析中，体重指数、年龄、烧伤的存在与否以及心脏手术均不影响 AKI 的风险。
IAH 与 AKI 风险相关，而这种关联不受年龄、体重指数、烧伤的存在与否或心脏手术的影响。
