Roux F X, Loty B, Brasnu D, Guillemin G
Service de Neurochirurgie, Hôpital Sainte-Anne, Paris.
Neurochirurgie. 1988;34(2):110-2.
Following experimental investigations on animals, small coral grafts have been utilized on patients since 1985 to fill in burr holes (42 patients). This first clinical experimental step has been satisfactory. Therefore, blocks of corals have since then been used as bone graft substitutes for anterior skull basis reconstruction (12 patients). Cheap and easily sterilized, coral implants have the advantage of being inert (99% of calcium carbonate), biodegradable and well reossified. They shorten surgical procedures by avoiding the use of iliac and/or costal grafts. No infectious complications have been noted.
在对动物进行实验研究之后，自1985年起已在患者身上使用小块珊瑚移植物来填充骨钻孔（42例患者）。这第一个临床实验步骤取得了令人满意的效果。因此，从那时起，珊瑚块就被用作颅骨前基底部重建的骨移植替代物（12例患者）。珊瑚植入物价格便宜且易于消毒，具有惰性（99%为碳酸钙）、可生物降解且能良好再骨化的优点。它们避免了使用髂骨和/或肋骨移植物，从而缩短了手术过程。未观察到感染性并发症。
