Division of General Surgery, Huntsman Cancer Institute, University of Utah, 1950 Circle of Hope, Suite 6405, Salt Lake City, UT 84112, USA.
Division of General Surgery, Huntsman Cancer Institute, University of Utah, 1950 Circle of Hope, Suite 6405, Salt Lake City, UT 84112, USA.
Surg Oncol Clin N Am. 2021 Jul;30(3):475-490. doi: 10.1016/j.soc.2021.02.004.
In addition to severe, life-limiting complications such as malignant bowel obstruction, fistulae, and malignant ascites, peritoneal carcinomatosis frequently causes life-impacting symptoms such as pain, nausea, anorexia, cachexia, and fatigue. A variety of medical, interventional, and surgical therapies are now available for management of both complications and symptoms. Although surgery in this population is often associated with a relatively high risk of morbidity and mortality, operative intervention can offer effective palliative treatment in appropriately selected patients. Early involvement of palliative care specialists as part of a multidisciplinary team is essential to providing optimal, holistic care of patients with peritoneal carcinomatosis.
除了恶性肠梗阻、瘘管和恶性腹水等严重的生命受限并发症外,腹膜癌病还常导致严重影响生活的症状,如疼痛、恶心、厌食、恶病质和疲劳。目前有多种医疗、介入和手术治疗方法可用于治疗并发症和症状。尽管该人群的手术通常与较高的发病率和死亡率相关,但手术干预可以为适当选择的患者提供有效的姑息治疗。姑息治疗专家作为多学科团队的一部分尽早参与,对于为腹膜癌病患者提供最佳的整体护理至关重要。