Aoyama Naoki
Department of Neurosurgery, JCHO Yokohama Central Hospital, Yokohama, Japan.
Br J Pain. 2021 May;15(2):199-212. doi: 10.1177/2049463720924704. Epub 2020 May 31.
The trigeminal nerve theory has been proposed as a pathophysiological mechanism of migraine; however, its association with the triggers of migraine remains unclear. Cervical disability such as neck pain and restricted cervical rotation, have been associated with not only cervicogenic headaches but also migraine. The presence of cervical disability could worsen of the migraine, and also the response to pharmacologic treatment may be reduced. The aim in this review is to highlight the involvement of cervical disability in migraine, considering contributing factors.
In recent years, evidence of neck pain complaints in migraine has been increasing. In addition, there is some recent evidence of cervical musculoskeletal impairments in migraine, as detected by physical assessment. However, the main question of whether neck pain or an associated cervical disability can act as an initial factor leading to migraine attacks still remains. Daily life imposes heavy loads on cervical structures (i.e. muscles, joints and ligaments), for instance, in the forward head position. The repetitive nociceptive stimulation initiating those cervical skeletal muscle positions may amplify the susceptibility to central migraine and contribute to chronicity via the trigeminal cervical complex.
Further studies are needed to explain the association between cervical disability as a source of pain and the development of migraine. However, evidence suggests that cervical disability needs to be considered in the prevention and treatment of migraine.
三叉神经理论已被提出作为偏头痛的一种病理生理机制;然而,其与偏头痛触发因素之间的关联仍不明确。颈部残疾,如颈部疼痛和颈椎旋转受限,不仅与颈源性头痛有关,也与偏头痛有关。颈部残疾的存在可能会使偏头痛恶化,而且药物治疗的反应可能会降低。本综述的目的是考虑相关因素,强调颈部残疾在偏头痛中的作用。
近年来,偏头痛患者颈部疼痛主诉的证据不断增加。此外,通过体格检查发现,近期有一些证据表明偏头痛患者存在颈部肌肉骨骼损伤。然而,颈部疼痛或相关的颈部残疾是否能作为导致偏头痛发作的初始因素这一主要问题仍然存在。日常生活会给颈部结构(即肌肉、关节和韧带)带来沉重负担,例如,在头部前倾的姿势下。引发这些颈部骨骼肌位置的重复性伤害性刺激可能会增加中枢性偏头痛的易感性,并通过三叉神经颈复合体导致慢性化。
需要进一步研究来解释作为疼痛来源的颈部残疾与偏头痛发生之间的关联。然而,有证据表明,在偏头痛的预防和治疗中需要考虑颈部残疾。