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2
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An investigation into the solution structure of the single-stranded DNA undecamer 5'd AAGTGTGATAT by means of nuclear Overhauser enhancement measurements.通过核Overhauser效应测量对单链DNA十一聚体5'd AAGTGTGATAT的溶液结构进行研究。
Eur Biophys J. 1984;11(2):95-102. doi: 10.1007/BF00276624.

本文引用的文献

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Negatively supercoiled plasmids contain left-handed Z-DNA segments as detected by specific antibody binding.通过特异性抗体结合检测发现，负超螺旋质粒含有左手Z-DNA片段。
Cell. 1982 Dec;31(2 Pt 1):309-18. doi: 10.1016/0092-8674(82)90124-6.
2
Right-handed and left-handed DNA: studies of B- and Z-DNA by using proton nuclear Overhauser effect and P NMR.右手螺旋和左手螺旋DNA：利用质子核Overhauser效应和磷核磁共振对B型和Z型DNA的研究
Proc Natl Acad Sci U S A. 1982 Mar;79(5):1413-7. doi: 10.1073/pnas.79.5.1413.
3
Proton nuclear Overhauser effect study of the structure of a deoxyoligonucleotide duplex in aqueous solution.水溶液中脱氧寡核苷酸双链体结构的质子核Overhauser效应研究。
Biochemistry. 1983 Apr 12;22(8):2019-25. doi: 10.1021/bi00277a044.
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Sequential resonance assignments in 1H NMR spectra of oligonucleotides by two-dimensional NMR spectroscopy.通过二维核磁共振光谱对寡核苷酸的1H NMR光谱进行顺序共振归属。
Biochemistry. 1984 Mar 27;23(7):1371-6. doi: 10.1021/bi00302a006.
5
1H NMR relaxation studies of the hydrogen-bonded imino protons of poly(dA-dT).聚（dA-dT）中氢键合亚氨基质子的1H NMR弛豫研究
Biochemistry. 1984 Feb 28;23(5):944-55. doi: 10.1021/bi00300a023.
6
Two-dimensional proton nuclear magnetic resonance investigation of the synthetic deoxyribonucleic acid decamer d(ATATCGATAT)2.合成脱氧核糖核酸十聚体d(ATATCGATAT)₂的二维质子核磁共振研究
Biochemistry. 1983 Dec 6;22(25):5943-51. doi: 10.1021/bi00294a038.
7
Nuclear Overhauser effect as a tool for the complete assignment of nonexchangeable proton resonances in short deoxyribonucleic acid helices.核Overhauser效应作为完全确定短脱氧核糖核酸螺旋中不可交换质子共振峰的一种工具。
Biochemistry. 1983 Oct 25;22(22):5194-200. doi: 10.1021/bi00291a020.
8
The chemistry and biology of left-handed Z-DNA.左手螺旋Z-DNA的化学与生物学
Annu Rev Biochem. 1984;53:791-846. doi: 10.1146/annurev.bi.53.070184.004043.
9
Nuclear Overhauser experiments at 500 MHz on the downfield proton spectrum of a ribonuclease-resistant fragment of 5S ribonucleic acid.在500兆赫频率下对5S核糖核酸的一种抗核糖核酸酶片段的低场质子光谱进行核Overhauser实验。
Biochemistry. 1983 May 24;22(11):2615-22. doi: 10.1021/bi00280a004.
10
Assignment of the non-exchangeable proton resonances of d(C-G-C-G-A-A-T-T-C-G-C-G) using two-dimensional nuclear magnetic resonance methods.使用二维核磁共振方法对d（C-G-C-G-A-A-T-T-C-G-C-G）的非交换质子共振进行归属
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1H核磁共振研究自互补十二聚体核苷酸d(TGCA)3的溶液结构

1H NMR study of the solution structure of the self-complementary dodecanucleotide d(TGCA)3.

作者信息

Stevens W C, Huang D H, Wells R D, Krishna N R

机构信息

Department of Biochemistry, School of Medicine, University of Alabama, Birmingham 35294.

出版信息

Nucleic Acids Res. 1988 Jul 25;16(14B):7133-43. doi: 10.1093/nar/16.14.7133.

DOI:10.1093/nar/16.14.7133
PMID:3405759
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC338356/
Abstract

The deoxyoligonucleotide d(TGCA)3 is a candidate for exhibiting unusual conformations. Its 1H NMR spectrum under low salt conditions has been obtained at 400 MHz and assigned using two-dimensional NMR techniques. The sugar puckers and glycosidic torsions have been determined by inspecting the relative intensities of the intranucleotide NOEs and COSY crosspeaks. At low electrolyte concentration (100 mM NaCl) the molecule exists as a right-handed duplex with twelve Watson-Crick base-pairs and deoxyribose moieties assuming the O1'-endo to C1'-exo pucker.

摘要

脱氧寡核苷酸d(TGCA)3是呈现异常构象的候选分子。已在400 MHz下获得其在低盐条件下的1H NMR谱，并使用二维NMR技术进行了归属。通过检查核苷酸内NOE和COSY交叉峰的相对强度确定了糖的折叠和糖苷扭转。在低电解质浓度（100 mM NaCl）下，该分子以具有十二个沃森-克里克碱基对的右手双链体形式存在，脱氧核糖部分呈现O1'-内向至C1'-外向折叠。