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2019冠状病毒病时代的院内心脏骤停发生率及预后:新加坡一家医院的观察性研究

In-hospital cardiac arrest incidence and outcomes in the era of COVID-19: an observational study in a Singapore hospital.

作者信息

Lyu Ting, Khan Faheem Ahmed, Sajeed Shanaz Matthew, Kansal Amit, Kansal Monika Gulati, Dhanvijay Shekhar, Tan Rou An, D'Souza Jared, Cendana Ian, Leong Patricia, Tan Chee Keat

机构信息

Department of Intensive Care Medicine, Ng Teng Fong General Hospital, National University Health System, 1 Jurong East Street 21, Singapore, 609606, Singapore.

Department of Intensive Care Medicine, the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China.

出版信息

Int J Emerg Med. 2021 May 31;14(1):33. doi: 10.1186/s12245-021-00356-7.

DOI:10.1186/s12245-021-00356-7
PMID:34058983
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8165958/
Abstract

BACKGROUND

COVID-19 pandemic has resulted in significant strain on healthcare resources and this requires diligent resource re-allocation. We aim to describe the incidence and outcomes of in-hospital cardiac arrest (IHCA) during this period as compared to non-pandemic period.

METHODS

We conducted a retrospective study in a tertiary care hospital in Singapore. The study compared the incidence and outcomes of code blue activations over a 3-month period from March to May 2020 (COVID-19 period) with the same months in 2019 (pre-COVID-19 period). The primary outcome of the study was the rate of survival to hospital discharge for IHCA. The secondary outcomes included incidence of all code blue activation per 1000 hospital admissions, incidence of IHCA per 1000 hospital admissions.

OUTCOMES

The rate of survival to hospital discharge for IHCA was 5.88% in the COVID-19 period as compared to 10.0% in the pre-COVID-19 period [odds ratio (OR), 0.72; 95% confidence interval (CI), 0.26-1.95]. Compared to pre-COVID-19 period, there were more IHCA incidences per 1000 hospital admissions in the COVID-19 period (1.86 vs 1.03; OR, 1.81; 95% CI, 0.78-4.41).

CONCLUSIONS

The study observed a trend towards higher incidence of IHCA and lower rate of survival to hospital discharge during COVID-19 pandemic compared to pre-COVID-19 period.

摘要

背景

新型冠状病毒肺炎疫情给医疗资源带来了巨大压力,这需要进行认真的资源重新分配。我们旨在描述这一时期院内心脏骤停(IHCA)的发生率及转归,并与非疫情时期进行比较。

方法

我们在新加坡一家三级医疗机构开展了一项回顾性研究。该研究比较了2020年3月至5月这3个月期间(新型冠状病毒肺炎时期)与2019年相同月份(新型冠状病毒肺炎疫情前时期)的蓝色急救代码激活的发生率及转归。该研究的主要结局是IHCA患者出院生存率。次要结局包括每1000例住院患者中所有蓝色急救代码激活的发生率、每1000例住院患者中IHCA的发生率。

结果

新型冠状病毒肺炎时期IHCA患者出院生存率为5.88%,而新型冠状病毒肺炎疫情前时期为10.0%[优势比(OR)为0.72;95%置信区间(CI)为0.26 - 1.95]。与新型冠状病毒肺炎疫情前时期相比,新型冠状病毒肺炎时期每1000例住院患者中IHCA的发生率更高(1.86比1.03;OR为1.81;95%CI为0.78 - 4.41)。

结论

该研究观察到,与新型冠状病毒肺炎疫情前时期相比,新型冠状病毒肺炎疫情期间IHCA的发生率有升高趋势,而出院生存率有降低趋势。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0888/8168320/5fa6cb0fe105/12245_2021_356_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0888/8168320/09f0185ba522/12245_2021_356_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0888/8168320/654e0cefcfcf/12245_2021_356_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0888/8168320/4626af13bef3/12245_2021_356_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0888/8168320/5fa6cb0fe105/12245_2021_356_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0888/8168320/09f0185ba522/12245_2021_356_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0888/8168320/654e0cefcfcf/12245_2021_356_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0888/8168320/4626af13bef3/12245_2021_356_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0888/8168320/5fa6cb0fe105/12245_2021_356_Fig4_HTML.jpg

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