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药用植物和有机硒对绵羊血矛线虫病的影响

Effects of Medicinal Plants and Organic Selenium against Ovine Haemonchosis.

作者信息

Komáromyová Michaela, Mravčáková Dominika, Petrič Daniel, Kucková Katarína, Babják Michal, Dolinská Michaela Urda, Königová Alžbeta, Maďarová Michaela, Pruszyńska-Oszmałek Ewa, Cieslak Adam, Čobanová Klaudia, Váradyová Zora, Várady Marián

机构信息

Institute of Parasitology, Slovak Academy of Sciences, Hlinkova 3, 040 01 Košice, Slovakia.

University of Veterinary Medicine and Pharmacy in Košice, Komenského 73, 041 81 Košice, Slovakia.

出版信息

Animals (Basel). 2021 May 5;11(5):1319. doi: 10.3390/ani11051319.

Abstract

The objective of this study was to determine the effect of traditional medicinal plants typical to Central Europe as well as organic selenium on increasing the resistance of lambs to gastrointestinal nematode (GIN) infection with 21 female lambs were infected with third-stage larvae of on the day (D) 0 and re-infected on D49 and D77. The animals were divided into three groups based on a treatment diet: a basal diet (control), a diet enriched with dry plants (Herbmix), and a diet enriched with selenized yeast (Selplex). The number of eggs per gram (EPG) of feces was quantified on D21, D28, D35, D42, D49, D56, D63, D70, D77, D84, D91, D98, D105, D112, and D119. The mean reductions in EPG on D28 were 43.4 and 28.6% for Selplex and Herbmix, respectively. The reduction in egg output was nearly uniform throughout the experiment for Selplex. However, for Herbmix the mean reduction was only 19.8% up to D91 and 46.1% after D91. Glutathione peroxidase activity in the blood from D35 to D98 was two to three-fold higher for Selplex than the other groups. Both supplements slowed the dynamics of GIN infection and gradually increased the resistance of lambs against ovine haemonchosis.

摘要

本研究的目的是确定中欧典型的传统药用植物以及有机硒对提高羔羊对胃肠道线虫(GIN)感染抵抗力的影响。21只雌性羔羊在第0天感染了第三期幼虫,并在第49天和第77天再次感染。根据治疗饮食将动物分为三组:基础饮食(对照组)、富含干植物的饮食(草药混合物)和富含硒酵母的饮食(Selplex)。在第21天、第28天、第35天、第42天、第49天、第56天、第63天、第70天、第77天、第84天、第91天、第98天、第105天、第112天和第119天对每克粪便中的虫卵数(EPG)进行定量。在第28天,Selplex和草药混合物的EPG平均降低率分别为43.4%和28.6%。在整个实验过程中,Selplex的虫卵产量降低几乎是均匀的。然而,对于草药混合物,直到第91天平均降低率仅为19.8%,第91天后为46.1%。从第35天到第98天,Selplex组血液中的谷胱甘肽过氧化物酶活性比其他组高两到三倍。两种补充剂都减缓了GIN感染的动态,并逐渐提高了羔羊对绵羊血矛线虫病的抵抗力。

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