Barcikowska Zofia, Rajkowska-Labon Elżbieta, Grzybowska Magdalena Emilia, Hansdorfer-Korzon Rita, Wąż Piotr, Zorena Katarzyna
Department of Immunobiology and Environment Microbiology, Medical University of Gdańsk, Dębinki 7, 80-211 Gdańsk, Poland.
Department of Physical Therapy, Medical University of Gdańsk, Dębinki 7, 80-211 Gdańsk, Poland.
Healthcare (Basel). 2021 May 21;9(6):617. doi: 10.3390/healthcare9060617.
The aim of the study was to evaluate the effect of manual therapy and the use of ibuprofen on the severity of dysmenorrhea and changes in the level of sex hormones in young women with dysmenorrhea. : The study included six women, aged 22 ± 2 years, with primary dysmenorrhea (PD). A physiotherapist examined the tenderness and flexibility of the muscles. The patients were subjected to a gynecological and physiotherapeutic examination; the concentrations of progesterone and 17-beta-estradiol were also determined. In subgroup A ( = 3), manual therapy was performed 3 × 45 min; in subgroup B ( = 3), the patients received ibuprofen 3 × 400 mg/day. : In subgroup A, all patients showed a decrease in the level of progesterone and an increase in the concentration of estradiol. In subgroup B, the concentration of progesterone and 17-beta estradiol decreased in two subjects. In subgroup A, manual therapy reduced the severity of headache, back pain, diarrhea, fatigue, and PMS. In subgroup B, the use of ibuprofen only alleviated back pain and fatigue. Moreover, in subgroup A, after the application of manual therapy, improvement in flexibility and pain relief of the examined muscles was demonstrated. On the other hand, in subgroup B, no improvement in flexibility or reduction in muscle soreness was found in patients who took ibuprofen. : Manual therapy may reduce menstrual pain in women with dysmenorrhea. However, the results need to be confirmed in studies conducted on a larger group of patients with dysmenorrhea.
该研究的目的是评估手法治疗和使用布洛芬对痛经年轻女性痛经严重程度以及性激素水平变化的影响。该研究纳入了6名年龄在22±2岁的原发性痛经（PD）女性。一名物理治疗师检查了肌肉的压痛和柔韧性。对患者进行了妇科和物理治疗检查；还测定了孕酮和17-β-雌二醇的浓度。在A亚组（n = 3）中，进行了3次每次45分钟的手法治疗；在B亚组（n = 3）中，患者每天服用3次每次400毫克的布洛芬。在A亚组中，所有患者的孕酮水平均下降，雌二醇浓度升高。在B亚组中，两名受试者的孕酮和17-β-雌二醇浓度下降。在A亚组中，手法治疗减轻了头痛、背痛、腹泻、疲劳和经前综合征的严重程度。在B亚组中，使用布洛芬仅缓解了背痛和疲劳。此外，在A亚组中，手法治疗后，所检查肌肉的柔韧性得到改善，疼痛减轻。另一方面，在B亚组中，服用布洛芬的患者未发现柔韧性改善或肌肉酸痛减轻。手法治疗可能减轻痛经女性的月经疼痛。然而，这些结果需要在对更大组痛经患者进行的研究中得到证实。
