Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale SS. Annunziata, 98168 Messina, Italy.
Shenzhen International Institute for Biomedical Research, 1301 Guanguang Rd. 3F Building 1-B, Silver Star Hi-Tech Park Longhua District, Shenzhen 518116, China.
Viruses. 2021 May 4;13(5):828. doi: 10.3390/v13050828.
Viral infections are responsible for several chronic and acute diseases in both humans and animals. Despite the incredible progress in human medicine, several viral diseases, such as acquired immunodeficiency syndrome, respiratory syndromes, and hepatitis, are still associated with high morbidity and mortality rates in humans. Natural products from plants or other organisms are a rich source of structurally novel chemical compounds including antivirals. Indeed, in traditional medicine, many pathological conditions have been treated using plant-derived medicines. Thus, the identification of novel alternative antiviral agents is of critical importance. In this review, we summarize novel phytochemicals with antiviral activity against human viruses and their potential application in treating or preventing viral disease.
病毒感染可导致人类和动物罹患多种慢性和急性疾病。尽管人类医学取得了令人难以置信的进步，但一些病毒病，如艾滋病、呼吸道综合征和肝炎，仍然导致人类发病率和死亡率居高不下。植物或其他生物的天然产物是结构新颖的化学化合物的丰富来源，包括抗病毒药物。事实上，在传统医学中，许多病理状况都使用植物源性药物进行治疗。因此，确定新型替代抗病毒药物至关重要。在这篇综述中，我们总结了具有抗人类病毒活性的新型植物化学物质及其在治疗或预防病毒病方面的潜在应用。
